SynthesisThe Pediatric infectious disease journal2017
Norovirus in Latin America: Systematic Review and Meta-analysis.
Synthesis in The Pediatric infectious disease journal, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 4 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
26 citing papers in PubMed, 4 syntheses or guidelines pooled it, 56 citations in OpenAlex.
- Pooled it
- Rotavirus vaccines in Africa and Norovirus genetic diversity in children aged 0 to 5 years old: a systematic review and meta-analysis : Rotavirus vaccines in Africa and Norovirus genetic diversity.BMC infectious diseases · 2024Pooled it
- Global prevalence of asymptomatic norovirus infection in outbreaks: a systematic review and meta-analysis.BMC infectious diseases · 2023Pooled it
- A systematic review and meta-analysis of the prevalence of norovirus in cases of gastroenteritis in developing countries.Medicine · 2017Pooled it
- Article
- Article
- Incidence of Norovirus-Associated Acute Gastroenteritis across Age Groups in a Peruvian Andean Community.The American journal of tropical medicine and hygiene · 2025Article
- Prevalence and genotype distribution of human norovirus infections in Ghana: A systematic review and meta-analysis.Environmental health insights · 2025Review
- Norovirus in children under 2 years of age: an epidemiological study in Panama during the COVID-19 pandemic.Frontiers in pediatrics · 2024Article
- Profiling of humoral immune responses to norovirus in children across Europe.Scientific reports · 2022Article
- High Prevalence and Diversity of Caliciviruses in a Community Setting Determined by a Metagenomic Approach.Microbiology spectrum · 2022Article
- Long-term dynamics ofPeerJ · 2021Article
- Molecular epidemiology of norovirus outbreaks in Argentina, 2013-2018.Journal of medical virology · 2020Article
- Etiology of acute gastroenteritis among children less than 5 years of age in Bucaramanga, Colombia: A case-control study.PLoS neglected tropical diseases · 2020Article
- Partial Genome Sequences of Human Norovirus Strains from Northeast Brazil.Microbiology resource announcements · 2020Article
- Absence of norovirus contamination in shellfish harvested and commercialized in the Northeast coast of Brazil.Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologica · 2020Article
- Prevalence and genetic diversity of viral gastroenteritis viruses in children younger than 5 years of age in Guatemala, 2014-2015.Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology · 2019Article
- Review
- Molecular detection and characterisation of sapoviruses and noroviruses in outpatient children with diarrhoea in Northwest Ethiopia.Epidemiology and infection · 2019Article
- Progress on norovirus vaccine research: public health considerations and future directions.Expert review of vaccines · 2018Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 2 countries.
Funding
Abstract
backgroundNoroviruses are increasingly recognized as a major cause of sporadic and epidemic acute gastroenteritis (AGE). Although there have been multiple studies published on norovirus epidemiology in Latin America, no comprehensive assessment of the role of norovirus has been conducted in the region. We aim to estimate the role of norovirus in the Latin American region through a systematic review and meta-analysis of the existing literature.
methodsWe carried out a literature search in MEDLINE, SciELO and LILACS. We included papers that provided information on the prevalence or incidence of norovirus (including seroprevalence studies and outbreaks), with a recruitment and/or follow-up period of at least 12 months and where the diagnosis of norovirus was confirmed by reverse transcription polymerase chain reaction. The data were pooled for meta-analysis to estimate the prevalence of norovirus AGE and norovirus asymptomatic infection with 95% confidence intervals (CIs).
resultsThirty-eight studies were included in the review. Overall, the prevalence of norovirus among AGE cases was 15% (95% CI: 13-18). By location, it was 15% in the community (95% CI: 11%-21%), 14% in outpatient settings (95% CI: 10%-19%) and 16% in hospital locations (95% CI: 12%-21%). The prevalence of norovirus among asymptomatic subjects was 8% (95% CI: 4-13). Norovirus GII.4 strains were associated with 37%-100% of norovirus AGE cases, but only 7% of norovirus asymptomatic detections.
conclusionsNoroviruses are associated with almost 1 out of every 6 hospitalizations because of acute diarrhea in children younger than 5 years of age in Latin America.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.