ArticleJournal of the American Chemical Society2016
Synthesis of Secondary Unsaturated Lactams via an Aza-Heck Reaction.
Article in Journal of the American Chemical Society, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
What it found
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
21 citing papers in PubMed, 80 citations in OpenAlex.
- Enantioselective rapid assembly of bis-heterocycles by sequential palladium-catalyzed aza-Heck cyclization coupling reaction.Science advances · 2026Article
- Asymmetric Synthesis of Quaternary Hydantoins via a Palladium-Catalyzed Aza-Heck Cyclization.Journal of the American Chemical Society · 2025Article
- Article
- Diastereospecific arylation and cascade deconstructive amidation/thioesterification of readily available lactam-fused bromolactones.RSC advances · 2023Article
- Cyclopropane-FusedJournal of the American Chemical Society · 2022Article
- Radical Aza-Heck Cyclization of Imidates via Energy Transfer, Electron Transfer, and Cobalt Catalysis.ACS catalysis · 2022Article
- Electrophilic Aminating Agents in Total Synthesis.Angewandte Chemie (International ed. in English) · 2021Review
- Alkyne Aminopalladation/Heck and Suzuki Cascades: An Approach to Tetrasubstituted Enamines.Chemistry (Weinheim an der Bergstrasse, Germany) · 2021Article
- Complex Polyheterocycles and the Stereochemical Reassignment of Pileamartine A via Aza-Heck Triggered Aryl C-H Functionalization Cascades.Journal of the American Chemical Society · 2021Article
- Total Synthesis of (±)-Impatien A via Aza-Heck Cyclization.Organic letters · 2021Article
- Tandem aza-Heck Suzuki and carbonylation reactions ofChemical science · 2021Article
- Concise Synthesis and Antimicrobial Evaluation of the Guanidinium Alkaloid Batzelladine D: Development of a Stereodivergent Strategy.Journal of the American Chemical Society · 2020Article
- Synthesis of Indolines and Derivatives by Aza-Heck Cyclization.Angewandte Chemie (International ed. in English) · 2019Article
- A Facile Direct Route to N-(Un)substituted Lactams by Cycloamination of Oxocarboxylic Acids without External Hydrogen.ChemSusChem · 2019Article
- Cross-Coupling of Heteroatomic Electrophiles.Chemical reviews · 2019Review
- Synthesis of N-H Bearing Imidazolidinones and Dihydroimidazolones Using Aza-Heck Cyclizations.Angewandte Chemie (International ed. in English) · 2018Article
- Pyrrolidines and Piperidines by Ligand-Enabled Aza-Heck Cyclizations and Cascades of N-(Pentafluorobenzoyloxy)carbamates.Angewandte Chemie (International ed. in English) · 2018Article
- Heck-like Reactions Involving Heteroatomic Electrophiles.European journal of organic chemistry · 2017Article
- Recent developments in the use of aza-Heck cyclizations for the synthesis of chiral N-heterocycles.Chemical science · 2017Article
- Mizoroki-Heck Cyclizations of Amide Derivatives for the Introduction of Quaternary Centers.Angewandte Chemie (International ed. in English) · 2017Article
Corrections and comments
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
Abstract
The preparation of unsaturated secondary lactams via the palladium-catalyzed cyclization of O-phenyl hydroxamates onto a pendent alkene is reported. This method provides rapid access to a broad range of lactams that are widely useful building blocks in alkaloid synthesis. Mechanistic studies support an aza-Heck-type pathway.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.