Evidence map›Paper›PMID 27754464›Full record

ArticleMolecules (Basel, Switzerland)2016

Coumarin Antifungal Lead Compounds from Millettia thonningii and Their Predicted Mechanism of Action.

Daniel M Ayine-Tora, Robert Kingsford-Adaboh, William A Asomaning, Jerry J E K Harrison, Felix C Mills-Robertson, Yahaya Bukari, Patrick O Sakyi, Sylvester Kaminta, Jóhannes Reynisson

Abstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Daniel M Ayine-ToraSchool of Chemical Sciences, University of Auckland, 23 Symonds Street, 1142 Auckland, New Zealand. dayi479@aucklanduni.ac.nz.
Robert Kingsford-AdabohDepartment of Chemistry, University of Ghana, LG 56, Legon-Accra, Ghana. kadabohs@yahoo.com.
William A AsomaningDepartment of Chemistry, University of Ghana, LG 56, Legon-Accra, Ghana. waasoman@ug.edu.gh.
Jerry J E K HarrisonDepartment of Chemistry, University of Ghana, LG 56, Legon-Accra, Ghana. harriebow@gmail.com.
Felix C Mills-RobertsonDepartment of Biochemistry and Biotechnology, Kwame Nkrumah University of Science and Technology, Kumasi, Ghana. mirobfc2002@yahoo.com.
Yahaya BukariBotany Department, University of Ghana, LG 55, Legon-Accra, Ghana. sparrowson@yahoo.com.
Patrick O SakyiDepartment of Chemistry, University of Ghana, LG 56, Legon-Accra, Ghana. poskeydinho@yahoo.com.
Sylvester KamintaCentre for Plant Medicine Research, 73, Mampong-Akuapem, Ghana. slykmt@yahoo.co.uk.
Jóhannes ReynissonSchool of Chemical Sciences, University of Auckland, 23 Symonds Street, 1142 Auckland, New Zealand. j.reynisson@auckland.ac.nz.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Fungal pathogens continue to pose challenges to humans and plants despite efforts to control them. Two coumarins, robustic acid and thonningine-C isolated from

Indexed as

Antifungal AgentsCandida albicansCatalytic DomainCoumarinsFungal ProteinsIsoflavonesMicrobial Sensitivity TestsMillettiaModels, MolecularMolecular Docking SimulationMolecular StructureProtein BindingSterol 14-DemethylaseStructure-Activity RelationshipAntifungal AgentsCoumarinsFungal ProteinsIsoflavonesrobustic acidSterol 14-DemethylaseCandida albicansCYP51isoflavonemolecular modellingnatural productsSclorotium

Identifiers

PMID27754464
PMCPMC6274499

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.