Evidence map›Paper›PMID 27753234›Full record

ArticleObesity (Silver Spring, Md.)2016

Atrial electrocardiography in obesity and hypertension: Clinical insights from the Polish-Norwegian Study (PONS).

Georgeta D Vaidean, Marta Manczuk, Jared W Magnani

Open access · bronzeAbstract read
In one paragraph

Article in Obesity (Silver Spring, Md.), 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
2.5field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 24 citations in OpenAlex.

  1. Pooled it
  2. Impact of Obesity on Atrial Electrophysiological Substrate.Journal of cardiovascular development and disease · 2023
    Review
  3. Article
  4. Article
  5. Electrocardiographic QRS duration is influenced by body mass index and sex.International journal of cardiology. Heart & vasculature · 2021
    Article
  6. Article
  7. Obesity and hypertension contribute to prolong QRS complex duration among middle-aged adults.Annals of noninvasive electrocardiology : the official journal of the International Society for Holter and Noninvasive Electrocardiology, Inc · 2019
    Article
  8. Body mass index related electrocardiographic findings in healthy young individuals with a normal body mass index.Netherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation · 2019
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors at 3 institutions in 2 countries.

Georgeta D VaideanInstitute for Translational Epidemiology, Icahn School of Medicine at Mount Sinai, New York, New York, USA.
Marta ManczukThe Cancer Epidemiology and Prevention Division, Cancer Center and Institute of Oncology, Warsaw, Poland.
Jared W MagnaniDepartment of Medicine, Division of Cardiology, UPMC Heart & Vascular Institute, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.
Greater Poland Cancer Center · PLIcahn School of Medicine at Mount Sinai · USUniversity of Pittsburgh Medical Center · US

Funding

Doris Duke Charitable Foundation 2015084
6 · The paper itself

Abstract

objectiveObesity and hypertension often coexist and represent risk factors for atrial fibrillation. This study hypothesized that their single and joint effects on atrial remodeling would be reflected in the PR interval and P-wave durations on electrocardiogram (ECG).

methodsThis cross-sectional analysis of a community-based study included 11,308 men and women age 45-64. Atrial indices were obtained from digital standard 12-lead resting ECG. Analyses were adjusted for traditional cardiovascular risk factors.

resultsBoth ECG indices displayed a progressive increase across anthropometric indices. Each 5-unit increment in body mass index (BMI) increased P-wave duration by 1.9 ms (95% CI 1.5-2.2) and PR interval by 2.4 ms (95% CI 1.9-3.0), with similar trends for central obesity, even among those without obesity by BMI. Both ECG indices displayed graded increases across levels of blood pressure control, including prehypertension. A joint effect of overweight and hypertension on both ECG indices was detected. P-wave duration or PR interval among people with obesity was not additionally increased by hypertension.

conclusionsP-wave indices increase in general and central obesity. Hypertension exerts an incremental effect in people with overweight but not in people with obesity. The study furthered the understanding of atrial remodeling in the setting of major atrial fibrillation risk factors.

Indexed as

Atrial FibrillationCross-Sectional StudiesElectrocardiographyFemaleHeart Conduction SystemHumansHypertensionMaleMiddle AgedNorwayObesityPolandRisk Factors

Identifiers

PMID27753234
PMCPMC5595141
OpenAlexW2535337775

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.