ArticleMovement disorders : official journal of the Movement Disorder Society2016
Clinical and demographic characteristics related to onset site and spread of cervical dystonia.
Article in Movement disorders : official journal of the Movement Disorder Society, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 1 of them a synthesis that pooled it.
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Who cites it
26 citing papers in PubMed, 1 synthesis or guideline pooled it, 46 citations in OpenAlex.
- Sensory Tricks in Dystonia: A Systematic Review and Nested Quantitative Synthesis.Brain and behavior · 2026Pooled it
- Factors influencing botulinum toxin response in cervical dystonia: a two-center GAS-based study.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2026Observational
- Preferential age-related striatal volume preservation in cervical dystonia.Journal of neurology · 2026Article
- Article
- Clinical and physiological characteristics of tremor in a large cohort of focal and segmental dystonia.Dystonia (Lausanne, Switzerland) · 2024Article
- An Empirical Comparison of Commonly Used Universal Rating Scales for Dystonia.Movement disorders clinical practice · 2023Article
- Article
- Article
- Isolated Cervical Dystonia: Diagnosis and Classification.Movement disorders : official journal of the Movement Disorder Society · 2023Review
- Anatomical categorization of isolated non-focal dystonia: novel and existing patterns using a data-driven approach.Dystonia (Lausanne, Switzerland) · 2023Article
- Current Guidelines for Classifying and Diagnosing Cervical Dystonia: Empirical Evidence and Recommendations.Movement disorders clinical practice · 2022Article
- Predictive modeling of spread in adult-onset isolated dystonia: Key properties and effect of tremor inclusion.European journal of neurology · 2021Article
- Botulinum Injections for Idiopathic Cervical Dystonia: a Longitudinal Study.Neurotoxicity research · 2021Article
- Head tremor and pain in cervical dystonia.Journal of neurology · 2021Article
- The Dystonia Coalition: A Multicenter Network for Clinical and Translational Studies.Frontiers in neurology · 2021Review
- The Use of Botulinum Toxin for Treatment of the Dystonias.Handbook of experimental pharmacology · 2021Article
- Medical and Surgical Treatments for Dystonia.Neurologic clinics · 2020Review
- Defining research priorities in dystonia.Neurology · 2020Review
- Risk of spread in adult-onset isolated focal dystonia: a prospective international cohort study.Journal of neurology, neurosurgery, and psychiatry · 2020Article
- Minor Structural Differences in the Cervical Spine Between Patients With Cervical Dystonia and Age-Matched Healthy Controls.Frontiers in neurology · 2020Article
Corrections and comments
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Authors and funding
29 authors at 20 institutions in 6 countries.
Funding
Abstract
backgroundClinical characteristics of isolated idiopathic cervical dystonia such as onset site and spread to and from additional body regions have been addressed in single-site studies with limited data and incomplete or variable dissociation of focal and segmental subtypes. The objectives of this study were to characterize the clinical characteristics and demographics of isolated idiopathic cervical dystonia in the largest standardized multicenter cohort.
methodsThe Dystonia Coalition, through a consortium of 37 recruiting sites in North America, Europe, and Australia, recruited 1477 participants with focal (60.7%) or segmental (39.3%) cervical dystonia on examination. Clinical and demographic characteristics were evaluated in terms of the body region of dystonia onset and spread.
resultsSite of dystonia onset was: (1) focal neck only (78.5%), (2) focal onset elsewhere with later segmental spread to neck (13.3%), and (3) segmental onset with initial neck involvement (8.2%). Frequency of spread from focal cervical to segmental dystonia (22.8%) was consistent with prior reports, but frequency of segmental onset with initial neck involvement was substantially higher than the 3% previously reported. Cervical dystonia with focal neck onset, more than other subtypes, was associated with spread and tremor of any type. Sensory tricks were less frequent in cervical dystonia with segmental components, and segmental cervical onset occurred at an older age.
conclusionsSubgroups had modest but significant differences in the clinical characteristics that may represent different clinical entities or pathophysiologic subtypes. These findings are critical for design and implementation of studies to describe, treat, or modify disease progression in idiopathic isolated cervical dystonia. © 2016 International Parkinson and Movement Disorder Society.
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