ArticleNatural products and bioprospecting2016
Clerodane Diterpenoids with Anti-hyperglycemic Activity from Tinospora crispa.
Article in Natural products and bioprospecting, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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Who cites it
5 citing papers in PubMed.
- Clerodane diterpenoid glycosides from the tuberous roots of Paratinospora sagittata: targeted isolation, structure characterization and immunomodulatory properties.Natural products and bioprospecting · 2026Article
- Chemical characterization and ATP-citrate lyase inhibitory activity study of clerodane diterpenoids from Tinospora crispa.Journal of natural medicines · 2026Article
- An updated and comprehensive review on the ethnomedicinal uses, phytochemistry, pharmacological activity and toxicological profile ofPhytochemistry reviews : proceedings of the Phytochemical Society of Europe · 2023Review
- Amelioration of hyperglycemia and hyperlipidemia in a high-fat diet-fed mice by supplementation of a developed optimized polyherbal formulation.3 Biotech · 2022Article
- Efficiency of Tinospora crispa against Culex quinquefasciatus larva.Environmental science and pollution research international · 2019Article
Corrections and comments
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Authors and funding
8 authors.
Funding
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Abstract
Four new clerodane diterpenoids, tinosporols A-C (2-4) and tinosporoside A (5), together with six known analogues were isolated from the vines of Tinospora crispa. Their structures were established by extensive spectroscopic analysis. The relative configuration at C-12 in the known diterpenoid borapetoside E (1), the major component of the plant, was firstly established with the aid of molecular model. Compound 1 significantly reduced serum glucose levels at dose-dependent manners in alloxan-induced hyperglycemic mice and db/db type 2 diabetic mice.
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Registered trials
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