Evidence map›Paper›PMID 27752928›Full record

ArticleJournal of molecular neuroscience : MN2016

Ghrelin-Induced Enhancement of Vasopressin and Oxytocin Secretion in Rat Neurohypophyseal Cell Cultures.

M Gálfi, M Radács, Zs Molnár, I Budai, G Tóth, A Pósa, K Kupai, Z Szalai, R Szabó, H A Molnár and 3 more

Abstract read
PubMed Publisher
In one paragraph

Article in Journal of molecular neuroscience : MN, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.1field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 13 citations in OpenAlex.

  1. Review
  2. Physiological Effect of Ghrelin on Body Systems.International journal of endocrinology · 2020
    Review
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 1 institution in 1 country.

M GálfiDepartment of Environmental Biology and Education, Gyula Juhász Faculty of Education, Institute of Applied Science, University of Szeged, Szeged, Hungary.
M RadácsDepartment of Environmental Biology and Education, Gyula Juhász Faculty of Education, Institute of Applied Science, University of Szeged, Szeged, Hungary.
Zs MolnárDepartment of Environmental Biology and Education, Gyula Juhász Faculty of Education, Institute of Applied Science, University of Szeged, Szeged, Hungary.
I BudaiDepartment of Environmental Biology and Education, Gyula Juhász Faculty of Education, Institute of Applied Science, University of Szeged, Szeged, Hungary.
G TóthDepartment of Medical Chemistry, Faculty of Medicine, University of Szeged, Szeged, Hungary.
A PósaDepartment of Physiology, Anatomy and Neurosciences, Faculty of Science and Informatics, University of Szeged, Szeged, Hungary.
K KupaiDepartment of Physiology, Anatomy and Neurosciences, Faculty of Science and Informatics, University of Szeged, Szeged, Hungary.
Z SzalaiDepartment of Physiology, Anatomy and Neurosciences, Faculty of Science and Informatics, University of Szeged, Szeged, Hungary.
R SzabóDepartment of Physiology, Anatomy and Neurosciences, Faculty of Science and Informatics, University of Szeged, Szeged, Hungary.
H A MolnárGyula Juhász Faculty of Education, Institute of Physical Education and Sport Sciences, University of Szeged, Szeged, Hungary.
J GardiFirst Department of Internal Medicine, Faculty of Medicine, University of Szeged, Szeged, Hungary.
Ferenc A LászlóDepartment of Physiology, Anatomy and Neurosciences, Faculty of Science and Informatics, University of Szeged, Szeged, Hungary. laszlo.a.ferenc@freemail.hu.
Cs VargaDepartment of Physiology, Anatomy and Neurosciences, Faculty of Science and Informatics, University of Szeged, Szeged, Hungary.
University of Szeged · HU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The effects of ghrelin on vasopressin and oxytocin secretion were studied in 13-14-day cell cultures of isolated rat neurohypophyseal tissue. The vasopressin and oxytocin contents of the supernatant were determined by radioimmunoassay after a 1- or 2-h incubation. Significantly increased levels of vasopressin and oxytocin production were detected in the cell culture media following ghrelin administration, depending on the ghrelin doses. The oxytocin level proved to be more elevated than that of vasopressin. The increase of vasopressin and oxytocin secretion could be totally blocked by previous administration of the ghrelin receptor antagonist ([D-Lys

Indexed as

ExocytosisAnimalsCell LineCells, CulturedGhrelinHormonesMaleNeuroendocrine CellsOligopeptidesOxytocinPituitary GlandRatsRats, WistarReceptors, GhrelinVasopressinsGhrelinGHRP-6, Lys(3)-HormonesOligopeptidesOxytocinReceptors, GhrelinVasopressinsGhrelinGhrelin receptor antagonistNeurohypophyseal cell cultureOxytocinVasopressin

Identifiers

PMID27752928
OpenAlexW2535343878

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.