ArticleClinical research in cardiology : official journal of the German Cardiac Society2017
Impact of cardiac comorbidities on early and 1-year outcome after percutaneous mitral valve interventions: data from the German transcatheter mitral valve interventions (TRAMI) registry.
Article in Clinical research in cardiology : official journal of the German Cardiac Society, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 2 of them syntheses that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
12 citing papers in PubMed, 2 syntheses or guidelines pooled it, 19 citations in OpenAlex.
- Edge-to-edge percutaneous mitral repair for functional ischaemic and non-ischaemic mitral regurgitation: a systematic review and meta-analysis.ESC heart failure · 2022Pooled it
- Functional status and quality of life after transcatheter mitral valve repair: a prospective cohort study and systematic review.Clinical research in cardiology : official journal of the German Cardiac Society · 2017Pooled it
- Competing Risks of Cardiac and Noncardiac Mortality in Patients With Secondary Mitral Regurgitation Undergoing Transcatheter Edge-to-Edge Repair.Journal of the American Heart Association · 2025Article
- Impact of the introduction of percutaneous edge-to-edge mitral valve reconstruction on clinical practice in Germany compared to surgical valve repair.Clinical research in cardiology : official journal of the German Cardiac Society · 2021Article
- Prognosis of persistent mitral regurgitation in patients undergoing transcatheter aortic valve replacement.Clinical research in cardiology : official journal of the German Cardiac Society · 2020Article
- Mitral valve leaflet repair with the new PASCAL system: early real-world data from a German multicentre experience.Clinical research in cardiology : official journal of the German Cardiac Society · 2020Article
- Invasive hemodynamics and cardiac biomarkers to predict outcomes after percutaneous edge-to-edge mitral valve repair in patients with severe heart failure.Clinical research in cardiology : official journal of the German Cardiac Society · 2019Article
- Predictors of mortality in ischaemic versus non-ischaemic functional mitral regurgitation after successful transcatheter mitral valve repair using MitraClip: results from two high-volume centres.Clinical research in cardiology : official journal of the German Cardiac Society · 2019Article
- Atrioventricular valve disease: challenges and achievements in percutaneous treatment.Clinical research in cardiology : official journal of the German Cardiac Society · 2018Review
- Mitral Valve Interventions in Structural Heart Disease.Current cardiology reports · 2018Review
- Cardiac surgery 2016 reviewed.Clinical research in cardiology : official journal of the German Cardiac Society · 2017Review
- Role of Echocardiography in Transcatheter Valvular Heart Disease Interventions.Current cardiology reports · 2017Review
Corrections and comments
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Authors and funding
13 authors at 7 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
aimsThe use of the MitraClip system has gained widespread acceptance for the treatment of patients with mitral regurgitation (MR) who are not suitable for the conventional surgery. This study sought to investigate the early and 1-year outcome after MitraClip therapy of patients with MR and cardiac comorbidities. METHODS AND
resultsOutcomes through 12-month follow-up of patients (n = 528) who underwent MitraClip implantation were obtained from the German transcatheter mitral valve interventions (TRAMI) registry. The majority of these patients (n = 409, 77.5 %) also suffered from coronary artery disease (CAD). Patients with a dilated cardiomyopathy (DCM, n = 65, 12.3 %) or concomitant valvular aortic disease (AV, n = 54, 10.2 %) were less frequent. Although the prevalent pathogenesis was functional MR, patients with DCM had significantly more frequent a functional MR (96.9 %) compared to patients with CAD (74.9 %) or AV (62.5 %, p < 0.001). Technical success was achieved in 97.5 % of patients. Procedural echocardiograms demonstrated in the vast majority of patients a reduction from severe MR III to mild MR I with no difference between the groups (p = 0.83). The peri-procedural complication rate was very low. At 30-day and 12-month follow-up, the majority of patients were in NYHA functional class II or lower. The rate of death, stroke, and myocardial infarction (MACCE) was comparable in the three patient groups during 12-month follow-up (DCM 26.9 %, CAD 30.3 % and AV 27.5 %, p = 0.85).
conclusionsThe MitraClip implantation is feasible and safe even in high-risk patients with MR and cardiac comorbidities.
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Registered trials
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