Evidence map›Paper›PMID 27752636›Full record

ArticleClinical and experimental emergency medicine2016

Cardiac physiologic regulation of sub-type specific adrenergic receptors in transgenic mice overexpressing β

Ka Eul Kim, Hyun-Jin Tae, Petrashevskaya Natalia, Jae-Chul Lee, Ji Hyeon Ahn, Joon Ha Park, In Hye Kim, Taek Geun Ohk, Chan Woo Park, Jun Hwi Cho and 1 more

Open access · diamondAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Clinical and experimental emergency medicine, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 2 countries.

Ka Eul KimDepartment of Biomedical Science, Research Institute of Bioscience and Biotechnology, Hallym University, Chuncheon, Korea.
Hyun-Jin TaeDepartment of Emergency Medicine, Kangwon National University School of Medicine, Chuncheon, Korea; Bio-Safety Research Institute, College of Veterinary Medicine, Chonbuk National University, Iksan, Korea.
Petrashevskaya NataliaCardioPulmonary Genomics Program, Departments of Medicine and Physiology, University of Maryland School of Medicine, Baltimore, MD, USA.
Jae-Chul LeeDepartment of Neurobiology, Kangwon National University School of Medicine, Chuncheon, Korea.
Ji Hyeon AhnDepartment of Neurobiology, Kangwon National University School of Medicine, Chuncheon, Korea.
Joon Ha ParkDepartment of Neurobiology, Kangwon National University School of Medicine, Chuncheon, Korea.
In Hye KimDepartment of Neurobiology, Kangwon National University School of Medicine, Chuncheon, Korea.
Taek Geun OhkDepartment of Emergency Medicine, Kangwon National University School of Medicine, Chuncheon, Korea.
Chan Woo ParkDepartment of Emergency Medicine, Kangwon National University School of Medicine, Chuncheon, Korea.
Jun Hwi ChoDepartment of Emergency Medicine, Kangwon National University School of Medicine, Chuncheon, Korea.
Moo-Ho WonDepartment of Neurobiology, Kangwon National University School of Medicine, Chuncheon, Korea.
Kangwon National University · KRKorea Research Institute of Bioscience and Biotechnology · KRUniversity of Maryland, Baltimore · US

Funding

PKCa Signaling Regulates Contractility and Heart FailureP50HL077101 · NHLBI · UNIVERSITY OF CINCINNATI · PI KRANIAS, EVANGELIA G · 2005 to 2009
$19.1M
NHLBI NIH HHS P50 HL077101
6 · The paper itself

Abstract

objectiveCombination of β

methodsIn this study, we performed hemodynamic evaluation by examining force frequency response (FFR), Frank-Starling relationship, and response to a non-selective β-AR agonist (isoproterenol) in hearts isolated from 6-month-old transgenic (TG) mice overexpressing β

resultsCardiac physiologic consequences of β

conclusionHemodynamic evaluation performed in the present showed a difference in β

Indexed as

Adrenergic receptorsChronotropicInotropicIsoproterenolTransgenic mice

Identifiers

PMID27752636
PMCPMC5065340
OpenAlexW2526139277

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.