Evidence map›Paper›PMID 27752191›Full record

ArticleGhana medical journal2016

Long-term continuous administration of a hydro-ethanolic extract of

Patrick Amoateng, Samuel Adjei, Dorcas Osei-Safo, Believe Ahedor, Seidu A Mahmood, Benoit B N'guessan, Isaac J Asiedu-Gyekye, Alexander K Nyarko

Open access · diamondAbstract read
PubMed Full text at PMC
In one paragraph

Article in Ghana medical journal, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.7field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 8 citations in OpenAlex.

  1. Frontiers in pharmacology · 2021
    Article
  2. Evidence-based complementary and alternative medicine : eCAM · 2021
    Article
  3. Experimental and therapeutic medicine · 2020
    Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Patrick AmoatengDepartment of Pharmacology and Toxicology, School of Pharmacy, College of Health Sciences, University of Ghana, P.O Box LG 43, Legon, Accra, Ghana.
Samuel AdjeiDepartment of Animal Experimentation, Noguchi Memorial Institute for Medical Research, College of Health Sciences, University of Ghana, P. O. Box LG581, Legon, Accra, Ghana.
Dorcas Osei-SafoDepartment of Chemistry, University of Ghana, P. O. Box LG56, Legon, Accra, Ghana.
Believe AhedorDepartment of Animal Experimentation, Noguchi Memorial Institute for Medical Research, College of Health Sciences, University of Ghana, P. O. Box LG581, Legon, Accra, Ghana.
Seidu A MahmoodPathology Unit, Department of Medical Laboratory Science, School of Biomedical & Allied Health Sciences, College of Health Sciences, University of Ghana, Legon, Accra, Ghana.
Benoit B N'guessanDepartment of Pharmacology and Toxicology, School of Pharmacy, College of Health Sciences, University of Ghana, P.O Box LG 43, Legon, Accra, Ghana.
Isaac J Asiedu-GyekyeDepartment of Pharmacology and Toxicology, School of Pharmacy, College of Health Sciences, University of Ghana, P.O Box LG 43, Legon, Accra, Ghana.
Alexander K NyarkoDepartment of Pharmacology and Toxicology, School of Pharmacy, College of Health Sciences, University of Ghana, P.O Box LG 43, Legon, Accra, Ghana.
University of Ghana · GHUniversity of Health and Allied Sciences · GH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundConflicting reports about the toxicity of

methodsThe toxicological evaluation of the extract (100, 300 and 1000 mgkg

resultsThe extract produced no mortality in the rats treated during the study period. Only SNE 100 mgkg

conclusionsThe findings suggest hydro-ethanolic extract of

fundingJointly supported by the International Foundation for Science, Stockholm, Sweden, through a grant (# F/5191-1) to Dr. Patrick Amoateng and the Office of Research, Innovation and Development (ORID), University of Ghana, Accra, Ghana, grant awarded to Dr. Patrick Amoateng (reference number: URF/6/ILG-002/2012-2013).

Indexed as

AnimalsAsteraceaeBilirubinBlood ProteinsDose-Response Relationship, DrugGhanaLeukocyte CountMaleNeutropeniaPlant ExtractsPotassiumRatsRats, Sprague-DawleySerum AlbuminToxicity Tests, ChronicBilirubinBlood ProteinsPlant ExtractsPotassiumSerum AlbuminhaematologicalhistopathologicalSprague-Dawley ratsSynedrella nodiflora

Identifiers

PMID27752191
PMCPMC5044797
OpenAlexW2536027497

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.