ArticleScientific reports2016
Acute and chronic gregarisation are associated with distinct DNA methylation fingerprints in desert locusts.
Article in Scientific reports, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
6 citing papers in PubMed, 1 synthesis or guideline pooled it.
- A systematic review of locust phase polyphenism: from proximate mechanisms to ecology and management.PeerJ · 2026Pooled it
- The Integrative Imperatives of Locust Phase Polyphenism Research: A Bibliometric Analysis.Integrative organismal biology (Oxford, England) · 2026Review
- Including population and environmental dynamic heterogeneities in continuum models of collective behaviour with applications to locust foraging and group structure.PLoS computational biology · 2025Article
- Epigenetic variation in animal populations: Sources, extent, phenotypic implications, and ecological and evolutionary relevance.Journal of biosciences · 2021Review
- Dnmt1 has an essential function despite the absence of CpG DNA methylation in the red flour beetle Tribolium castaneum.Scientific reports · 2018Article
- Facilitation of environmental adaptation and evolution by epigenetic phenotype variation: insights from clonal, invasive, polyploid, and domesticated animals.Environmental epigenetics · 2017Review
Corrections and comments
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Authors and funding
3 authors.
Funding
Abstract
Desert locusts (Schistocerca gregaria) show a dramatic form of socially induced phenotypic plasticity known as phase polyphenism. In the absence of conspecifics, locusts occur in a shy and cryptic solitarious phase. Crowding with conspecifics drives a behavioural transformation towards gregariousness that occurs within hours and is followed by changes in physiology, colouration and morphology, resulting in the full gregarious phase syndrome. We analysed methylation-sensitive amplified fragment length polymorphisms (MS-AFLP) to compare the effect of acute and chronic crowding on DNA methylation in the central nervous system. We find that crowd-reared and solitary-reared locusts show markedly different neural MS-AFLP fingerprints. However, crowding for a day resulted in neural MS-AFLP fingerprints that were clearly distinct from both crowd-reared and uncrowded solitary-reared locusts. Our results indicate that changes in DNA methylation associated with behavioural gregarisation proceed through intermediate states that are not simply partial realisations of the endpoint states.
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Registered trials
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