ArticleScientific reports2016
Genetic and pathogenic characterisation of 11 avian reovirus isolates from northern China suggests continued evolution of virulence.
Article in Scientific reports, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 1 of them a synthesis that pooled it.
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Who cites it
24 citing papers in PubMed, 1 synthesis or guideline pooled it, 40 citations in OpenAlex.
- Avian Orthoreoviruses: A Systematic Review of Their Distribution, Dissemination Patterns, and Genotypic Clustering.Viruses · 2024Pooled it
- Article
- Novel multigene molecular characterization of avian reovirus strains and associated embryonic pathogenicity.Journal of virology · 2026Article
- Navigating the Complexity: Advancing Diagnostic Strategies for Avian Reovirus in Chinese Poultry.Animals : an open access journal from MDPI · 2026Review
- Development of a quadruplex RT-qPCR for the detection of avian leukosis virus, chicken infectious anemia virus, avian reovirus, and fowl adenovirus.Frontiers in veterinary science · 2026Article
- Genomic characterization and pathogenicity assessment of a novel strain of duck reovirus identified in China.Frontiers in microbiology · 2026Article
- Phylogenetic Analysis and Pathogenicity of Avian Reoviruses Isolated from Viral Arthritis Cases in China 2010-2024.Veterinary sciences · 2025Article
- Simultaneous detection and partial molecular characterization of five RNA viruses associated with enteric disease in chickens: chicken astrovirus, avian nephritis virus, infectious bronchitis virus, avian rotavirus a and avian orthoreovirus, via multiplex RT-qPCR.Frontiers in veterinary science · 2025Article
- Review
- Whole Genomic Constellation of Avian Reovirus Strains Isolated from Broilers with Arthritis in North Carolina, USA.Viruses · 2023Article
- Article
- Article
- Molecular and pathological investigation of avian reovirus (ARV) in Egypt with the assessment of the genetic variability of field strains compared to vaccine strains.Frontiers in microbiology · 2023Article
- Avian Reoviruses From Wild Birds Exhibit Pathogenicity to Specific Pathogen Free Chickens by Footpad Route.Frontiers in veterinary science · 2022Article
- Article
- Isolation and Molecular Characteristics of a Novel Recombinant Avian Orthoreovirus From Chickens in China.Frontiers in veterinary science · 2021Article
- Molecular Characterization of a Novel Budgerigar Fledgling Disease Virus Strain From Budgerigars in China.Frontiers in veterinary science · 2021Article
- Seroprevalence and risk factors of avian reovirus in backyard chickens in different areas of Mymensingh district in Bangladesh.Journal of advanced veterinary and animal research · 2020Article
- Sequencing and phylogenetic analysis of partial S1 genes of avian orthoreovirus isolates in Shandong province during 2015-2017.Poultry science · 2020Article
- Molecular detection of Mycoplasma synoviae and avian reovirus infection in arthritis and tenosynovitis lesions of broiler and breeder chickens in Santa Catarina State, Brazil.Journal of the South African Veterinary Association · 2019Article
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Authors and funding
8 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Avian reovirus (ARV) infections characterised by severe arthritis, tenosynovitis, pericarditis, and depressed growth have become increasingly frequent in recent years. In this study, we isolated and identified 11 ARV field strains from chickens with viral arthritis and reduced growth in northern China. Comparative analysis of the σC nucleotide and amino acid sequences demonstrated that all isolates, except LN05 and JS01, were closely related to ARV S1133 and clustered in the first genetic lineage. LN05 and JS01 strains were clustered in the third lineage with the ARV 138 strain. Using S1133 as a reference, five isolates were selected to infect specific-pathogen-free chickens, and we found that the recent isolated Chinese ARV strains had higher replication ability in vivo and caused enhanced mortality than the S1133 strain. These findings suggest that the pathogenicity of Chinese ARVs has been changing in recent years and disease control may become more difficult. This study provides genetic and pathogenic characterisations of ARV strains isolated in northern China and calls for a sustained surveillance of ARV infection in China in order to support a better prevention and control of the disease.
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