ArticleThe Journal of thoracic and cardiovascular surgery2016
Repair of large airway defects with bioprosthetic materials.
Article in The Journal of thoracic and cardiovascular surgery, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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Who cites it
19 citing papers in PubMed, 32 citations in OpenAlex.
- Surgery for Benign Tracheoesophageal Fistula: Analysis of Short- and Long-Term Outcomes.World journal of surgery · 2026Article
- Preclinical and human tracheal replacement with aortic grafts: a narrative review.Mediastinum (Hong Kong, China) · 2026Review
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- Multidisciplinary management of a complex case of postesophagectomy tracheoesophageal fistula.JTCVS techniques · 2025Article
- Endoscopic management of tracheoesophageal fistulas: a narrative review.Mediastinum (Hong Kong, China) · 2025Review
- Treatment of Esophago-Airway Fistula after Esophageal Resection.Healthcare (Basel, Switzerland) · 2023Article
- Mesenchymal Stromal Cell Therapy for Thoracic Surgeons: An Update.Journal of personalized medicine · 2023Review
- Article
- Intraoperative methods for wrapping anastomoses after airway reconstruction: a case series.Translational lung cancer research · 2022Article
- Development and clinical translation of tubular constructs for tracheal tissue engineering: a review.European respiratory review : an official journal of the European Respiratory Society · 2021Review
- Regenerative medicine approaches for the management of respiratory tract fistulas.Stem cell research & therapy · 2020Review
- A novel reconstruction technique of a tracheal defect in the emergent setting using a thymus flap in a patient with tracheoinnominate artery fistula.Surgical case reports · 2020Article
- Current indications for the intrathoracic transposition of the omentum.Journal of cardiothoracic surgery · 2019Review
- Artificial lung.Journal of thoracic disease · 2018Review
- Regenerative medicine in cardiothoracic surgery: do the benefits outweigh the risks?Journal of thoracic disease · 2018Article
- A reassessment of tracheal substitutes-a systematic review.Annals of cardiothoracic surgery · 2018Review
- Bioprosthetics and repair of complex aerodigestive defects.Annals of cardiothoracic surgery · 2018Article
- Repair of large airway defects with bioprosthetic materials.Journal of thoracic disease · 2017Article
- Prosthetic reconstruction of the trachea: A historical perspective.World journal of clinical cases · 2017Review
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivePatients with complicated airway defects that exceed the limits of primary repair represent a challenging clinical problem and require alternative techniques for repair. The aim of this study was to evaluate bioprosthetic reconstruction of large tracheal and bronchial defects.
methodsRetrospective chart review of patients treated at a single tertiary center from 2008 to 2015 who underwent repair of tracheal or bronchial defects with a bioprosthetic device, namely aortic homograft or acellular dermal matrix.
resultsEight patients, 3 men and 5 women with a mean age of 54 ± 13 years, underwent closure of complex central airway defects with bioprosthetic material. All but 1 patient underwent prior operative or stenting procedures. Three patients had isolated airway defects, whereas 5 had fistulas between the airway and enteric tract. Defects involved the membranous wall of the trachea (n = 5), the anterior wall of the trachea (n = 1), or the main stem bronchus (n = 2). Five reconstructions were with aortic homograft and 3 with acellular dermal matrix. Bioprosthetic material was buttressed with muscle flap (n = 4), omentum (n = 2), or left unbuttressed (n = 2). The airway defect was successfully closed in all patients. There was no postoperative mortality or recurrence of the airway defect in short-term follow-up. Two patients required debridement of granulation tissue and 1 additional patient required airway balloon dilation. Progression of underlying metastatic disease explained the majority of long-term mortality (75%).
conclusionsBioprosthetic materials represent a viable option for management of large airway defects, including airway-enteric fistulae, that exceed the limits of primary repair.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.