ArticleBMC biology2016
Morphological and Transcriptomic Analysis of a Beetle Chemosensory System Reveals a Gnathal Olfactory Center.
Article in BMC biology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers.
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38 citing papers in PubMed, 112 citations in OpenAlex.
- Anatomical Investigation Reveals a Second Olfactory System in Locusts.The Journal of comparative neurology · 2026Article
- Expanding the sensory horizon: chemosensory receptors beyond traditional olfactory and taste organs in insects.Science China. Life sciences · 2026Review
- Identification of candidate chemosensory receptors based on transcriptome analysis in the monophagous insect Protegira songi (Lepidoptera, Noctuidae).BMC genomics · 2026Article
- Article
- Life-stage dependent behavior mimics chemosensory repertoire diversity in a belowground, specialist herbivore.G3 (Bethesda, Md.) · 2025Article
- Ultrastructural and Functional Organization of Maxillary Palps in Ladybird Species (Coleoptera: Coccinellidae) With Different Feeding Preferences.Microscopy research and technique · 2025Article
- Antennal Transcriptome Screening and Identification of Chemosensory Proteins in the Double-Spine European Spruce Bark Beetle,International journal of molecular sciences · 2024Article
- Article
- De novo assembly and annotation of Popillia japonica's genome with initial clues to its potential as an invasive pest.BMC genomics · 2024Article
- Editorial: Recent advances in insect olfaction: characterization of neural circuits from sensory input to motor output.Frontiers in cellular neuroscience · 2023Article
- Anatomic and neurochemical analysis of the palpal olfactory system in the red flour beetleFrontiers in cellular neuroscience · 2023Article
- Copy number changes in co-expressed odorant receptor genes enable selection for sensory differences in drosophilid species.Nature ecology & evolution · 2022Article
- Review
- Article
- The Genome ofGenes · 2022Article
- Odor-Induced Vomiting Is Combinatorially Triggered by Palp Olfactory Receptor Neurons That Project to the Lobus Glomerulatus in Locust Brain.Frontiers in physiology · 2022Article
- Candidate Chemosensory Genes Identified in the Adult Antennae ofFrontiers in physiology · 2022Article
- Antennal transcriptome analysis of chemosensory genes in the cowpea beetle, Callosobruchus maculatus (F.).PloS one · 2022Article
- Mutually Exclusive Expression of Closely Related Odorant-Binding Proteins 9A and 9B in the Antenna of the Red Flour BeetleBiomolecules · 2021Article
- Metamorphic development of the olfactory system in the red flour beetle (Tribolium castaneum, HERBST).BMC biology · 2021Article
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Authors and funding
11 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe red flour beetle Tribolium castaneum is an emerging insect model organism representing the largest insect order, Coleoptera, which encompasses several serious agricultural and forest pests. Despite the ecological and economic importance of beetles, most insect olfaction studies have so far focused on dipteran, lepidopteran, or hymenopteran systems.
resultsHere, we present the first detailed morphological description of a coleopteran olfactory pathway in combination with genome-wide expression analysis of the relevant gene families involved in chemoreception. Our study revealed that besides the antennae, also the mouthparts are highly involved in olfaction and that their respective contribution is processed separately. In this beetle, olfactory sensory neurons from the mouthparts project to the lobus glomerulatus, a structure so far only characterized in hemimetabolous insects, as well as to a so far non-described unpaired glomerularly organized olfactory neuropil in the gnathal ganglion, which we term the gnathal olfactory center. The high number of functional odorant receptor genes expressed in the mouthparts also supports the importance of the maxillary and labial palps in olfaction of this beetle. Moreover, gustatory perception seems equally distributed between antenna and mouthparts, since the number of expressed gustatory receptors is similar for both organs.
conclusionsOur analysis of the T. castaneum chemosensory system confirms that olfactory and gustatory perception are not organotopically separated to the antennae and mouthparts, respectively. The identification of additional olfactory processing centers, the lobus glomerulatus and the gnathal olfactory center, is in contrast to the current picture that in holometabolous insects all olfactory inputs allegedly converge in the antennal lobe. These findings indicate that Holometabola have evolved a wider variety of solutions to chemoreception than previously assumed.
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