ArticleRedox report : communications in free radical research2017
Multiple cryotherapy applications attenuate oxidative stress following skeletal muscle injury.
Article in Redox report : communications in free radical research, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed, 27 citations in OpenAlex.
- Multiple Cryotherapy Attenuates Oxi-Inflammatory Response Following Skeletal Muscle Injury.International journal of environmental research and public health · 2020Trial
- Multiple Cold-Water Immersions Attenuate Muscle Damage but not Alter Systemic Inflammation and Muscle Function Recovery: A Parallel Randomized Controlled Trial.Scientific reports · 2018Trial
- Effects of cold water immersion versus active recovery on oxidative stress, redox gene expression and mitochondrial adaptations after strength training.Experimental physiology · 2026Article
- Cold as a therapeutic frontier: place of whole-body cryotherapy in modern medicine.European journal of applied physiology · 2026Review
- Targeting Vascular Impairment, Neuroinflammation, and Oxidative Stress Dynamics with Whole-Body Cryotherapy in Multiple Sclerosis Treatment.International journal of molecular sciences · 2024Review
- Beyond Tissue replacement: The Emerging role of smart implants in healthcare.Materials today. Bio · 2023Review
- Influence of Intermittent Cold Stimulations on CREB and Its Targeting Genes in Muscle: Investigations into Molecular Mechanisms of Local Cryotherapy.International journal of molecular sciences · 2020Article
- Don't Lose Your Cool With Cryotherapy: The Application of Phase Change Material for Prolonged Cooling in Athletic Recovery and Beyond.Frontiers in sports and active living · 2020Review
- Local cryotherapy minimally impacts the metabolome and transcriptome of human skeletal muscle.Scientific reports · 2017Article
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Corrections and comments
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Authors and funding
7 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesTo investigate the effects of multiple cryotherapy applications after muscle injury on markers of oxidative stress.
methodsFollowing cryolesion-induced skeletal muscle injury in rats, ice was applied at the injured site for 30 minutes, three times per day, on the day of injury, and for 2 days after injury. To determine the effect of the cryotherapy treatment on markers of oxidative stress, biochemical analyses were performed 3, 7, and 14 days after injury.
resultsCompared with non-treated animals, cryotherapy reduced dichlorofluorescein at 7 and 14 days post-injury and thiobarbituric acid reactive substances levels at 3 and 7 days post-injury (P < 0.05). Additionally, cryotherapy maintained methyl thiazol tetrazolium reduction levels compared to the control group at all analyzed time points (P > 0.05), whereas non-treated groups demonstrated lower levels than the control group (P < 0.05). Superoxide dismutase activity at 7 and 14 days post-injury and catalase activity at 3 days post-injury were lower in cryotherapy groups compared with non-treated groups (P < 0.05). Cryotherapy prevented the reduction of non-protein thiol levels and maintained within control group level, at 3 days post-injury (P = 0.92). DISCUSSION: Cryotherapy reduced the production of reactive oxygen species after muscle injury, resulting in an attenuated response of the antioxidant system. These findings suggest that using multiple cryotherapy applications is efficient to reduce oxidative stress.
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