ReviewMass spectrometry reviews2018
Mass spectrometric strategies for the investigation of biomarkers of illicit drug use in wastewater.
Review in Mass spectrometry reviews, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
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Who cites it
24 citing papers in PubMed.
- Targeted LC-MS/MS method for quantifying respiratory pharmaceuticals in wastewater.Environmental science : water research & technology · 2026Article
- Data Hidden in Sewage: Advanced Methods for Identification and Quantification of Synthetic Cannabinoids in Urban Wastewater.Molecules (Basel, Switzerland) · 2026Review
- The first report from Ankara on the presence of xylazine abuse in blood and urine samples using a validated LC-HRMS method.International journal of legal medicine · 2025Article
- Analysis of Wastewater Samples to Explore Community Substance Use in the United States: Pilot Correlative and Machine Learning Study.JMIR formative research · 2023Article
- Development and validation of a liquid chromatography tandem mass spectrometry method for the analysis of 53 benzodiazepines in illicit drug samples.Forensic chemistry (Amsterdam, Netherlands) · 2023Article
- Trends and challenges in analytical chemistry for multi-analysis of illicit drugs employing wastewater-based epidemiology.Analytical and bioanalytical chemistry · 2023Article
- Wastewater-based epidemiology for the assessment of population exposure to chemicals: The need for integration with human biomonitoring for global One Health actions.Journal of hazardous materials · 2023Article
- Biomarker selection strategies based on compound stability in wastewater-based epidemiology.Environmental science and pollution research international · 2023Review
- Long-term monitoring of drug consumption patterns during the COVID-19 pandemic in a small-sized community in Brazil through wastewater-based epidemiology.Chemosphere · 2022Article
- Qualitative fingerprinting of psychoactive pharmaceuticals, illicit drugs, and related human metabolites in wastewater: A year-long study from Riga, Latvia.Journal of environmental chemical engineering · 2022Article
- Consequence of COVID-19 occurrences in wastewater with promising recognition and healing technologies: A review.Environmental progress & sustainable energy · 2022Review
- Recent Advances in the Use of Surface-Enhanced Raman Scattering for Illicit Drug Detection.Sensors (Basel, Switzerland) · 2022Review
- Molecular imaging of humain hair with MeV-SIMS: A case study of cocaine detection and distribution in the hair of a cocaine user.PloS one · 2022Article
- Identification of biomarkers in wastewater-based epidemiology: Main approaches and analytical methods.Trends in analytical chemistry : TRAC · 2021Review
- "Waste Not, Want Not" - Leveraging Sewer Systems and Wastewater-Based Epidemiology for Drug Use Trends and Pharmaceutical Monitoring.Journal of medical toxicology : official journal of the American College of Medical Toxicology · 2021Article
- Isotope pattern deconvolution as a successful alternative to calibration curve for application in wastewater-based epidemiology.Analytical and bioanalytical chemistry · 2021Article
- Evaluation of Illicit Drug Consumption by Wastewater Analysis Using Polar Organic Chemical Integrative Sampler as a Monitoring Tool.Frontiers in chemistry · 2021Review
- Nanomaterial-based aptamer sensors for analysis of illicit drugs and evaluation of drugs consumption for wastewater-based epidemiology.Trends in analytical chemistry : TRAC · 2020Review
- Spatio-temporal assessment of illicit drug use at large scale: evidence from 7 years of international wastewater monitoring.Addiction (Abingdon, England) · 2020Article
- Household Contamination with Methamphetamine: Knowledge and Uncertainties.International journal of environmental research and public health · 2019Review
Corrections and comments
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Authors and funding
13 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The analysis of illicit drugs in urban wastewater is the basis of wastewater-based epidemiology (WBE), and has received much scientific attention because the concentrations measured can be used as a new non-intrusive tool to provide evidence-based and real-time estimates of community-wide drug consumption. Moreover, WBE allows monitoring patterns and spatial and temporal trends of drug use. Although information and expertise from other disciplines is required to refine and effectively apply WBE, analytical chemistry is the fundamental driver in this field. The use of advanced analytical techniques, commonly based on combined chromatography-mass spectrometry, is mandatory because the very low analyte concentration and the complexity of samples (raw wastewater) make quantification and identification/confirmation of illicit drug biomarkers (IDBs) troublesome. We review the most-recent literature available (mostly from the last 5 years) on the determination of IDBs in wastewater with particular emphasis on the different analytical strategies applied. The predominance of liquid chromatography coupled to tandem mass spectrometry to quantify target IDBs and the essence to produce reliable and comparable results is illustrated. Accordingly, the importance to perform inter-laboratory exercises and the need to analyze appropriate quality controls in each sample sequence is highlighted. Other crucial steps in WBE, such as sample collection and sample pre-treatment, are briefly and carefully discussed. The article further focuses on the potential of high-resolution mass spectrometry. Different approaches for target and non-target analysis are discussed, and the interest to perform experiments under laboratory-controlled conditions, as a complementary tool to investigate related compounds (e.g., minor metabolites and/or transformation products in wastewater) is treated. The article ends up with the trends and future perspectives in this field from the authors' point of view. © 2016 Wiley Periodicals, Inc. Mass Spec Rev 37:258-280, 2018.
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