ArticleNature2016
The mechanism of force transmission at bacterial focal adhesion complexes.
Article in Nature, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 79 papers.
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Who cites it
79 citing papers in PubMed.
- Discovery of PilU as a second type IV pilus retraction motor inJournal of bacteriology · 2026Article
- Cell polarity control by an unconventional G-protein complex in bacteria.Nature communications · 2026Article
- Distinct motors, shared mechanics: unifying principles of microbial gliding.Journal of bacteriology · 2026Review
- Milestones in the development ofJournal of bacteriology · 2025Review
- Article
- RABiTPy: an open-source Python software for rapid, AI-powered bacterial tracking and analysis.BMC bioinformatics · 2025Article
- Review
- Structural model of a bacterial focal adhesion complex.Communications biology · 2025Article
- The Tol Pal system integrates maintenance of the three layered cell envelope.npj antimicrobials and resistance · 2024Review
- A lytic transglycosylase connects bacterial focal adhesion complexes to the peptidoglycan cell wall.eLife · 2024Article
- A lytic transglycosylase connects bacterial focal adhesion complexes to the peptidoglycan cell wall.bioRxiv : the preprint server for biology · 2024Article
- A geometrical theory of gliding motility based on cell shape and surface flow.Proceedings of the National Academy of Sciences of the United States of America · 2024Article
- A molecular switch controls assembly of bacterial focal adhesions.Science advances · 2024Article
- Mutation Rate and Effective Population Size of the Model Cooperative Bacterium Myxococcus xanthus.Genome biology and evolution · 2024Article
- Noninvasive Analysis of Peptidoglycan from Living Animals.Bioconjugate chemistry · 2024Article
- Article
- Multi-scale dynamic imaging reveals that cooperative motility behaviors promote efficient predation in bacteria.Nature communications · 2023Article
- Flagellar polymorphism-dependent bacterial swimming motility in a structured environment.Biophysics and physicobiology · 2023Article
- New biochemistry in the Rhodanese-phosphatase superfamily: emerging roles in diverse metabolic processes, nucleic acid modifications, and biological conflicts.NAR genomics and bioinformatics · 2023Article
- Unmasking of the von Willebrand A-domain surface adhesin CglB at bacterial focal adhesions mediates myxobacterial gliding motility.Science advances · 2023Article
19 more citing papers are in PubMed but not listed here.
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17 authors.
Funding
Abstract
Various rod-shaped bacteria mysteriously glide on surfaces in the absence of appendages such as flagella or pili. In the deltaproteobacterium Myxococcus xanthus, a putative gliding motility machinery (the Agl-Glt complex) localizes to so-called focal adhesion sites (FASs) that form stationary contact points with the underlying surface. Here we show that the Agl-Glt machinery contains an inner-membrane motor complex that moves intracellularly along a right-handed helical path; when the machinery becomes stationary at FASs, the motor complex powers a left-handed rotation of the cell around its long axis. At FASs, force transmission requires cyclic interactions between the molecular motor and the adhesion proteins of the outer membrane via a periplasmic interaction platform, which presumably involves contractile activity of motor components and possible interactions with peptidoglycan. Our results provide a molecular model of bacterial gliding motility.
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