SynthesisMedicine2016
Physical activity and endometriosis risk in women with infertility or pain: Systematic review and meta-analysis.
Synthesis in Medicine, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
25 citing papers in PubMed, 3 syntheses or guidelines pooled it, 55 citations in OpenAlex.
- Transgender and gender diverse individuals embodying endometriosis: a systematic review.Frontiers in medicine · 2024Pooled it
- Effect of physical activity and exercise on endometriosis-associated symptoms: a systematic review.BMC women's health · 2021Pooled it
- Environmental Risk Factors for Endometriosis: An Umbrella Review of a Meta-Analysis of 354 Observational Studies With Over 5 Million Populations.Frontiers in medicine · 2021Pooled it
- The effects of physical activity on female fertility: a narrative review.Journal of assisted reproduction and genetics · 2026Review
- Article
- Review
- Longitudinal measurements of NO-mediated vasodilation and physical activity over 1 yr following endometriosis excision surgery: a passive experiment.Journal of applied physiology (Bethesda, Md. : 1985) · 2025Article
- Life behaviors, educational attainment, and risk for endometriosis: a Mendelian randomization study.Archives of medical science : AMS · 2025Article
- Exploring the Influence of IL-8, IL-10, Patient-Reported Pain, and Physical Activity on Endometriosis Severity.Diagnostics (Basel, Switzerland) · 2024Article
- Dysmenorrhea pattern in adolescences informing adult endometriosis.BMC public health · 2024Article
- Physical Activity in Women with Endometriosis: Less or More Compared with a Healthy Control?International journal of environmental research and public health · 2023Article
- Characterization and risk factors for unexplained female infertility in Sudan: A case-control study.World journal of methodology · 2023Article
- The effect of physical activity on fertility: a mini-review.F&S reports · 2023Article
- Women infertility and common mental disorders: A cross-sectional study from North India.PloS one · 2023Article
- Does Quality of Care (QoC) Perception Influence the Quality of Life (QoL) in Women with Endometriosis? Results from an Italian Nationwide Survey during Covid Pandemic.International journal of environmental research and public health · 2022Article
- Observational
- Impact of lifestyle and diet on endometriosis: a fresh look to a busy corner.Przeglad menopauzalny = Menopause review · 2022Review
- Overview of the Effect of Complementary Medicine on Treating or Mitigating the Risk of Endometriosis.Revista brasileira de ginecologia e obstetricia : revista da Federacao Brasileira das Sociedades de Ginecologia e Obstetricia · 2021Review
- Lifestyle and Chronic Pain in the Pelvis: State of the Art and Future Directions.Journal of clinical medicine · 2021Review
- Voluntary Wheel Running Reduces Vesicle Development in an Endometriosis Animal Model Through Modulation of Immune Parameters.Frontiers in reproductive health · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe potential association between endometriosis and physical activity (PA) has been suggested in several epidemiological studies.We aimed to establish whether PA influences endometriosis risk.
methodsMEDLINE and EMBASE were searched using "physical activity" OR "exercise" combined with "endometriosis," in Medical Subject Headings and free text. We selected original articles in English, published up to April 2016, evaluating the association between endometriosis and recent or past PA (case-control or cohort studies). References of retrieved papers were reviewed. We computed summary odds ratios (ORs) of endometriosis for recent and past PA.
resultsSix case-control and 3 cohort studies included 3355 cases for recent PA and 4600 cases for past PA. The summary OR for endometriosis according to PA level, calculated by the random-effect model, was 0.85 [95% confidence interval (CI) 0.67-1.07] for any recent versus no PA. As compared to no recent PA, ORs for low and moderate/high PA were 1.00 (95% CI: 0.68-1.28) and 0.75 (95% CI: 0.53-1.07), respectively.
conclusionsThough it suggests that PA may reduce the risk of endometriosis, this meta-analysis does not conclusively support the hypothesis. Whether our findings are really explained by the benefit of exercise at molecular and endocrine level, or related to confounding mechanisms, such as study design, choice of controls, and PA potentially improving pain, needs to be further investigated.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.