Evidence map›Paper›PMID 27748850›Full record

ReviewMolecular medicine reports2016

Occupational exposure to carcinogens: Benzene, pesticides and fibers (Review).

Luca Falzone, Andrea Marconi, Carla Loreto, Sabrina Franco, Demetrios A Spandidos, Massimo Libra

Open access · hybridAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Molecular medicine reports, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 46 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
46citing papers in PubMed, 2 pooled it
7.2field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

46 citing papers in PubMed, 2 syntheses or guidelines pooled it, 117 citations in OpenAlex.

  1. Occupational benzene exposure and risk of kidney and bladder cancers: a systematic review and meta-analysis.European journal of cancer prevention : the official journal of the European Cancer Prevention Organisation (ECP) · 2025
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  18. Role ofPathophysiology : the official journal of the International Society for Pathophysiology · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Luca FalzoneDepartment of Biomedical and Biotechnological Sciences, Section of General and Clinical Pathology and Oncology, University of Catania, I‑95124 Catania, Italy.
Andrea MarconiSection of Occupational Medicine, Department of Clinical and Experimental Medicine, University of Catania, I‑95124 Catania, Italy.
Carla LoretoDepartment of Biomedical and Biotechnological Sciences, Human Anatomy and Histology Section, School of Medicine, University of Catania, I‑95124 Catania, Italy.
Sabrina FrancoDepartment of Medical, Surgical and Advanced Technology Sciences 'G.F. Ingrassia', University of Catania, I‑95124 Catania, Italy.
Demetrios A SpandidosLaboratory of Clinical Virology, Medical School, University of Crete, Heraklion 71003, Greece.
Massimo LibraDepartment of Biomedical and Biotechnological Sciences, Section of General and Clinical Pathology and Oncology, University of Catania, I‑95124 Catania, Italy.
University of Catania · ITUniversity of Crete · GR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

It is well known that the occupational exposure to contaminants and carcinogens leads to the development of cancer in exposed workers. In the 18th century, Percivall Pott was the first to hypothesize that chronic exposure to dust in the London chimney sweeps was associated with an increased risk of developing cancer. Subsequently a growing body of evidence indicated that other physical factors were also responsible for oncogenic mutations. Over the past decades, many carcinogens have been found in the occupational environment and their presence is often associated with an increased incidence of cancer. Occupational exposure involves several factors and the association between carcinogens, occupational exposure and cancer is still unclear. Only a fraction of factors is recognized as occupational carcinogens and for each factor, there is an increased risk of cancer development associated with a specific work activity. According to the International Agency for Research on Cancer (IARC), the majority of carcinogens are classified as 'probable' and 'possible' human carcinogens, while, direct evidence of carcinogenicity is provided in epidemiological and experimental studies. In the present review, exposures to benzene, pesticides and mineral fibers are discussed as the most important cancer risk factors during work activities.

Indexed as

BenzeneCarcinogensHumansNeoplasmsOccupational ExposurePesticidesRisk FactorsBenzeneCarcinogensPesticides

Identifiers

PMID27748850
PMCPMC5101963
OpenAlexW2528181337

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.