Evidence map›Paper›PMID 27748712›Full record

ReviewTopics in magnetic resonance imaging : TMRI2016

Click Chemistry in the Development of Contrast Agents for Magnetic Resonance Imaging.

Sudath Hapuarachchige, Dmitri Artemov

Abstract readReview
In one paragraph

Review in Topics in magnetic resonance imaging : TMRI, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Expanding the Genetic Code for Neuronal Studies.Chembiochem : a European journal of chemical biology · 2020
    Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Sudath Hapuarachchige*Division of Cancer Imaging Research, The Russell H. Morgan Department of Radiology and Radiological Science †Department of Oncology, The Sidney Kimmel Comprehensive Cancer Center, The Johns Hopkins University School of Medicine, Baltimore, MD.
Dmitri Artemov

Funding

MR Pharmacoangiography-Vascular Modulation of DeliveryR01CA097310 · NCI · JOHNS HOPKINS UNIVERSITY · PI ARTEMOV, DMITRI · 2003 to 2005
$977k
NCI NIH HHS R01 CA097310
6 · The paper itself

Abstract

Click chemistry provides fast, convenient, versatile, and reliable chemical reactions that take place between pairs of functional groups of small molecules that can be purified without chromatographic methods. Due to the fast kinetics and low or no elimination of byproducts, click chemistry is a promising approach that is rapidly gaining acceptance in drug discovery, radiochemistry, bioconjugation, and nanoscience applications. Increasing use of click chemistry in synthetic procedures or as a bioconjugation technique in diagnostic imaging is occurring because click reactions are fast, provide a quantitative yield, and produce a minimal amount of nontoxic byproducts. This review summarizes the recent application of click chemistry in magnetic resonance imaging and discusses the directions for applying novel click reactions and strategies for further improving magnetic resonance imaging performance.

Indexed as

Click ChemistryMagnetic Resonance ImagingContrast MediaHumansMolecular StructureContrast Media

Identifiers

PMID27748712
PMCPMC5082715

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.