Evidence map›Paper›PMID 27748684›Full record

ArticleEpidemiology (Cambridge, Mass.)2017

Maternal Exposure to Aeroallergens and the Risk of Early Delivery.

Eric Lavigne, Antonio Gasparrini, David M Stieb, Hong Chen, Abdool S Yasseen, Eric Crighton, Teresa To, Scott Weichenthal, Paul J Villeneuve, Sabit Cakmak and 2 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Epidemiology (Cambridge, Mass.), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Article
  3. The Changing Climate and Pregnancy Health.Current environmental health reports · 2022
    Review
  4. Article
  5. Article
  6. Aeroallergens in Canada: Distribution, Public Health Impacts, and Opportunities for Prevention.International journal of environmental research and public health · 2018
    Review
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Eric LavigneFrom the aAir Health Science Division, Health Canada, Ottawa, Ontario, Canada; bSchool of Epidemiology, Public Health and Preventive Medicine, University of Ottawa, Ottawa, Ontario, Canada; cDepartment of Social and Environmental Health Research, London School of Hygiene & Tropical Medicine, London, United Kingdom; dPopulation Studies Division, Health Canada, Canada; ePublic Health Ontario, Toronto, Ontario, Canada; fDalla Lana School of Public Health, University of Toronto, Toronto, Ontario, Canada; gInstitute for Clinical Evaluative Sciences, Ontario, Canada; hOttawa Hospital Research Institute, Ottawa, Ontario, Canada; iBetter Outcomes Registry and Network Ontario, Ottawa, Ontario, Canada; jChildren's Hospital of Eastern Ontario Research Institute, Ottawa, Ontario, Canada; kDepartment of Geography, University of Ottawa, Ottawa, Ontario, Canada; lChild Health Evaluative Sciences, The Hospital for Sick Children, Toronto, Ontario, Canada; mDepartment of Epidemiology, Biostatistics and Occupational Health, McGill University, Montreal, Quebec, Canada; nCHAIM Research Centre, Carleton University, Ottawa, Ontario, Canada; and oAerobiology Research Laboratories, Ottawa, Ontario, Canada; and pDepartment of Obstetrics and Gynecology, University of Ottawa, Ottawa, ON, Canada.
Antonio Gasparrini
David M Stieb
Hong Chen
Abdool S Yasseen
Eric Crighton
Teresa To
Scott Weichenthal
Paul J Villeneuve
Sabit Cakmak
Frances Coates
Mark Walker

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundDaily changes in aeroallergens during pregnancy could trigger early labor, but few investigations have evaluated this issue. This study aimed to investigate the association between exposure to aeroallergens during the week preceding birth and the risk of early delivery among preterm and term pregnancies.

methodsWe identified data on 225,234 singleton births that occurred in six large cities in the province of Ontario, Canada, from 2004 to 2011 (April to October) from a birth registry. We obtained daily counts of pollen grains and fungal spores from fixed-site monitoring stations in each city and assigned them to pregnancy period of each birth. Associations between exposure to aeroallergens in the preceding week and risk of delivery among preterm (<37 gestational weeks), early-term (37-38 weeks), and full-term (≥39 weeks) pregnancies were evaluated with Cox regression models, adjusting for maternal characteristics, meteorologic parameters, and air pollution concentrations, and pooled across the six cities.

resultsThe risk of delivery increased by 3% per interquartile range width (IQRw = 22.1 grains/m) increase in weed pollen the day before birth among early-term (hazard ratio [HR] = 1.03; 95% confidence interval [CI]: 1.01, 1.05) and full-term pregnancies (HR = 1.03; 95% CI: 1.01, 1.04). Exposure to fungal spores cumulated over 0 to 2 lagged days was associated with increased risk of delivery among full-term pregnancies only (HR = 1.07; 95% CI: 1.01, 1.12). We observed no associations among preterm deliveries.

conclusionsIncreasing concentrations of ambient weed pollen and fungal spores may be associated with earlier delivery among term births.

Indexed as

AllergensPollenSpores, FungalAdultAir PollutionCitiesEnvironmental ExposureFemaleHumansMaternal ExposureOntarioPregnancyPremature BirthProportional Hazards ModelsRisk FactorsYoung AdultAllergens

Identifiers

PMID27748684
PMCPMC5380107

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.