ArticleScientific reports2016
Targeted suppression of autoreactive CD8
Open access · goldAbstract read
In one paragraph
Article in Scientific reports, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
1.2field-weighted citation impact, top 21% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed, 34 citations in OpenAlex.
- Entry Without Expression: Internalisation Does Not Predict mRNA Translation for Targeted Lipid Nanoparticles.Small science · 2026Article
- Generation of T cells with reduced off-target cross-reactivities by engineering co-signalling receptors.Nature biomedical engineering · 2026Article
- A Method for High-Throughput Screening of Monoclonal Antibody Internalization Using a DNA/Protein Molecular Staple.Small methods · 2025Article
- Long-term respiratory outcomes in school-aged children born before 32 weeks of gestation.European journal of pediatrics · 2025Observational
- CD8α and CD70 mark human natural killer cell populations which differ in cytotoxicity.Frontiers in immunology · 2025Article
- The TCR and LCK: foundations for T-cell activation and therapeutic innovation.Frontiers in immunology · 2025Review
- Shortwave-Infrared-Emitting Nanoprobes for CD8 Targeting and In Vivo Imaging of Cytotoxic T Cells in Breast Cancer.Advanced nanobiomed research · 2024Article
- Structure, function, and immunomodulation of the CD8 co-receptor.Frontiers in immunology · 2024Review
- CD8 coreceptor engagement of MR1 enhances antigen responsiveness by human MAIT and other MR1-reactive T cells.The Journal of experimental medicine · 2022Article
- Immuno-Imaging (PET/SPECT)-Quo Vadis?Molecules (Basel, Switzerland) · 2022Review
- Structural assessment of HLA-A2-restricted SARS-CoV-2 spike epitopes recognized by public and private T-cell receptors.Nature communications · 2022Article
- Nasal administration of anti-CD3 monoclonal antibody modulates effector CD8+ T cell function and induces a regulatory response in T cells in human subjects.Frontiers in immunology · 2022Article
- CD8 coreceptor-mediated focusing can reorder the agonist hierarchy of peptide ligands recognized via the T cell receptor.Proceedings of the National Academy of Sciences of the United States of America · 2021Article
- The CD8 T Cell-Epstein-Barr Virus-B Cell Trialogue: A Central Issue in Multiple Sclerosis Pathogenesis.Frontiers in immunology · 2021Review
- Public and private human T-cell clones respond differentially to HCMV antigen when boosted by CD3 copotentiation.Blood advances · 2020Article
- Morpholino-induced exon skipping stimulates cell-mediated and humoral responses to dystrophin in mdx mice.The Journal of pathology · 2019Article
- Anti-CD8 monoclonal antibody-mediated depletion alters the phenotype and behavior of surviving CD8+ T cells.PloS one · 2019Article
- Multiple Sclerosis: Mechanisms of Disease and Strategies for Myelin and Axonal Repair.Neurologic clinics · 2018Review
- Cytomegalovirus-Specific CD8+ T-Cells With Different T-Cell Receptor Affinities Segregate T-Cell Phenotypes and Correlate With Chronic Graft-Versus-Host Disease in Patients Post-Hematopoietic Stem Cell Transplantation.Frontiers in immunology · 2018Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
19 authors at 7 institutions in 3 countries.
Mathew ClementDivision of Infection and Immunity, Cardiff University, Cardiff CF14 4XN, UK.
James A PearsonDivision of Infection and Immunity, Cardiff University, Cardiff CF14 4XN, UK.
Stephanie GrasInfection and Immunity Program and Department of Biochemistry and Molecular Biology, Biomedicine Discovery Institute, Monash University, Clayton, Victoria 3800, Australia.
Hugo A van den BergMathematics Institute, University of Warwick, Coventry CV4 7AL, UK.
Anya LissinaFaculty of Health Sciences, University of Bristol, Bristol BS8 1TD, UK.
Sian Llewellyn-LaceyDivision of Infection and Immunity, Cardiff University, Cardiff CF14 4XN, UK.
Mark D WillisDivision of Psychological Medicine and Clinical Neuroscience, Cardiff University, Cardiff CF14 4XN, UK.
Tamsin DockreeDivision of Infection and Immunity, Cardiff University, Cardiff CF14 4XN, UK.
James E McLarenDivision of Infection and Immunity, Cardiff University, Cardiff CF14 4XN, UK.
Julia Ekeruche-MakindeMucosal Infection and Immunity Group, Department of Medicine, Imperial College London, London SW7 2AZ, UK.
Emma GostickDivision of Infection and Immunity, Cardiff University, Cardiff CF14 4XN, UK.
Neil P RobertsonDivision of Psychological Medicine and Clinical Neuroscience, Cardiff University, Cardiff CF14 4XN, UK.
Jamie RossjohnDivision of Infection and Immunity, Cardiff University, Cardiff CF14 4XN, UK.
Scott R BurrowsQIMR Berghofer Medical Research Institute, Brisbane, QLD 4029, Australia.
David A PriceDivision of Infection and Immunity, Cardiff University, Cardiff CF14 4XN, UK.
F Susan WongDivision of Infection and Immunity, Cardiff University, Cardiff CF14 4XN, UK.
Mark PeakmanDepartment of Immunobiology, King's College London, London SE1 9RT, UK.
Ania SkoweraDepartment of Immunobiology, King's College London, London SE1 9RT, UK.
Linda WooldridgeFaculty of Health Sciences, University of Bristol, Bristol BS8 1TD, UK.
Cardiff University · GBAustralian Regenerative Medicine Institute · AUKing's College London · GBUniversity of Bristol · GBImperial College London · GBQIMR Berghofer Medical Research Institute · AUUniversity of Warwick · GB
Funding
Wellcome Trust 100326/Z/12/ZWellcome Trust WT079848MA
Abstract
CD8
Indexed as
AnimalsAntibodiesAutoimmune DiseasesCD8 AntigensCD8-Positive T-LymphocytesCell LineEpitopesHistocompatibility Antigens Class IHumansImmunosuppression TherapyIslets of LangerhansLigandsLymphocyte ActivationMiceMice, Inbred NODMice, TransgenicAntibodiesCD8 AntigensEpitopesHistocompatibility Antigens Class ILigandsPeptidesReceptors, Antigen, T-Cell
Identifiers
What OpenQuestion holds
Textmetadata
LicenceCC BY
Read underepoch 390
Registered trials
None linked
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.