ArticleThe Indian journal of medical research2016
Spectrum of AIDS defining & non-AIDS defining malignancies in north India.
Article in The Indian journal of medical research, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.
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Who cites it
10 citing papers in PubMed, 1 synthesis or guideline pooled it, 14 citations in OpenAlex.
- HIV and neoplasms: What do we know so far?Einstein (Sao Paulo, Brazil) · 2023Pooled it
- Perceptions of integrating cervical cancer screening with HIV and sexual and reproductive health services: results from serial multiple methods studies among health workers and women in Zimbabwe.Reproductive health · 2025Article
- Human immunodeficiency virus-related renal cell carcinoma: a 13.5-year experience.AIDS research and therapy · 2025Article
- Human immunodeficiency virus-related renal cell carcinoma: a retrospective study of 19 cases.Infectious agents and cancer · 2021Article
- Survival after cancer diagnosis in a cohort of HIV-positive individuals in Latin America.Infectious agents and cancer · 2018Article
- Prevalence of HIV in Patients with Malignancy and of Malignancy in HIV Patients in a Tertiary Care Center from North India.Current HIV research · 2018Article
- Cervical cancer in Zimbabwe: a situation analysis.The Pan African medical journal · 2017Article
- Trends in malignancies among patients having human immunodeficiency virus infection attending a tertiary care hospital in southwest India.Medical journal, Armed Forces IndiaArticle
- Giant pleomorphic sarcoma of the tongue base - a cured clinical case report and literature review.Romanian journal of morphology and embryology = Revue roumaine de morphologie et embryologieReview
- Spectrum of malignancies among human immunodeficiency virus-infected patients at a tertiary level human immunodeficiency virus-anti-retroviral therapy center in a North Indian hospital.Indian journal of sexually transmitted diseases and AIDSArticle
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
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Abstract
BACKGROUND &
objectivesThere is scarcity of data on the frequency of malignancies in HIV infected individuals from India. The objective of this study was to determine the type and frequency of malignancies in HIV infected individuals attending a tertiary care hospital in north India.
methodsThe study design included retrospective analysis of data of all HIV infected individuals registered in the Immunodeficiency clinic from December 2009 to December 2011 and a prospective analysis of HIV infected individuals registered from January 2012 to April 2013. The clinical details and treatment outcomes of all individuals diagnosed to have AIDS defining and non-AIDS defining malignancies were recorded.
resultsRecords of 2880 HIV infected individuals were reviewed. Thirty one (19 males, 12 females) individuals were diagnosed to have malignancy. AIDS defining malignancy was found in the form of non-Hodgkin's lymphoma in 12 individuals and cervical cancer in six women. Non-AIDS defining malignancies included Hodgkin's lymphoma (n=2); and chronic myelogenous leukaemia, carcinoma base of tongue, carcinoma larynx, carcinoma bronchus, sinonasal carcinoma, ovarian carcinoma, anal carcinoma, carcinoma urinary bladder, pleomorphic sarcoma, parathyroid adenoma, and renal cell carcinoma in one individual each. Mean CD4+cell count prior to ART initiation was 250 ± 195.6 (median: 187; range, 22-805) cells/μl and at the time of diagnosis of malignancy was 272 ± 202 (median: 202; range, 15-959) cells/μl. The mean CD4+ count of individuals with AIDS defining malignancy was significantly lower when compared with non-AIDS defining malignancy (P<0.001). Fourteen individuals were alive and on regular follow up, 15 had died and two cases were lost to follow up. INTERPRETATION &
conclusionsThe frequency of malignancies in HIV infected patients at our centre was 1 per cent, with non-Hodgkin's lymphoma being the commonest. Further studies need to be done to document similar data from different parts of the country.
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