ArticleDevelopmental science2018
Functional connectivity differences in autism during face and car recognition: underconnectivity and atypical age-related changes.
Article in Developmental science, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 3 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
28 citing papers in PubMed, 3 syntheses or guidelines pooled it, 43 citations in OpenAlex.
- Neural dysfunctions associated with atypical memory in ASD: an ALE meta-analysis.Frontiers in psychiatry · 2026Pooled it
- Brain correlates of declarative memory atypicalities in autism: a systematic review of functional neuroimaging findings.Molecular autism · 2023Pooled it
- A quantitative meta-analysis of face recognition deficits in autism: 40 years of research.Psychological bulletin · 2021Pooled it
- Investigating Social Competence in a Pilot Randomized Clinical Trial of a Theatre-Based Intervention Enhanced for Adults with Autism Spectrum Disorder.Journal of autism and developmental disorders · 2025Trial
- E/I imbalance and internal noise cause weak neural representations and face recognition challenges in ASD.Communications biology · 2026Article
- Development and psychometric validation of a novel, self-report visual processing questionnaire (ViPro-SR) for neurodivergent adults.Current psychology (New Brunswick, N.J.) · 2026Article
- Overlapping and distinct intrinsic connectivity of hippocampal and triple networks in autistic individuals with and without a comorbid condition of ADHD.Frontiers in psychiatry · 2026Article
- Ultra-high resolution imaging of laminar thickness in face-selective cortex in autism.Cognitive, affective & behavioral neuroscience · 2025Article
- A multimodal neural signature of face processing in autism within the fusiform gyrus.Nature. Mental health · 2025Article
- Commercial Wearables for the Management of People with Autism Spectrum Disorder: A Review.Biosensors · 2024Review
- Age-related differences in the intrinsic connectivity of the hippocampus and ventral temporal lobe in autistic individuals.Frontiers in human neuroscience · 2024Article
- Neurobiological correlates and attenuated positive social intention attribution during laughter perception associated with degree of autistic traits.Journal of neural transmission (Vienna, Austria : 1996) · 2023Article
- Diminished Repetition Suppression Reveals Selective and Systems-Level Face Processing Differences in ASD.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2023Article
- Age differences and brain maturation provide insight into heterogeneous results in autism spectrum disorder.Frontiers in human neuroscience · 2022Review
- The Effect of Comorbid Attention-Deficit/Hyperactivity Disorder Symptoms on Face Memory in Children with Autism Spectrum Disorder: Insights from Transdiagnostic Profiles.Brain sciences · 2021Article
- Performance of machine learning classification models of autism using resting-state fMRI is contingent on sample heterogeneity.Neural computing & applications · 2021Article
- The Development of Brain Network in Males with Autism Spectrum Disorders from Childhood to Adolescence: Evidence from fNIRS Study.Brain sciences · 2021Article
- Face individual identity recognition: a potential endophenotype in autism.Molecular autism · 2020Article
- Looking beyond the face area: lesion network mapping of prosopagnosia.Brain : a journal of neurology · 2019Article
- A Longitudinal Study of Local Gyrification Index in Young Boys With Autism Spectrum Disorder.Cerebral cortex (New York, N.Y. : 1991) · 2019Article
Corrections and comments
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Authors and funding
7 authors at 3 institutions in 2 countries.
Funding
Abstract
Face recognition abilities improve between adolescence and adulthood over typical development (TD), but plateau in autism, leading to increasing face recognition deficits in autism later in life. Developmental differences between autism and TD may reflect changes between neural systems involved in the development of face encoding and recognition. Here, we focused on whole-brain connectivity with the fusiform face area (FFA), a well-established face-preferential brain region. Older children, adolescents, and adults with and without autism completed the Cambridge Face Memory Test, and a matched car memory test, during fMRI scanning. We then examined task-based functional connectivity between the FFA and the rest of the brain, comparing autism and TD groups during encoding and recognition of face and car stimuli. The autism group exhibited underconnectivity, relative to the TD group, between the FFA and frontal and primary visual cortices, independent of age. Underconnectivity with the medial and rostral lateral prefrontal cortex was face-specific during encoding and recognition, respectively. Conversely, underconnectivity with the L orbitofrontal cortex was evident for both face and car encoding. Atypical age-related changes in connectivity emerged between the FFA and the R temporoparietal junction, and R dorsal striatum for face stimuli only. Similar differences in age-related changes in autism emerged for FFA connectivity with the amygdala across both face and car recognition. Thus, underconnectivity and atypical development of functional connectivity may lead to a less optimal face-processing network in the context of increasing general and social cognitive deficits in autism.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.