Trial reportJournal of orthopaedic research : official publication of the Orthopaedic Research Society2017
Predictors of knee joint loading after anterior cruciate ligament reconstruction.
Trial report in Journal of orthopaedic research : official publication of the Orthopaedic Research Society, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
21 citing papers in PubMed, 1 synthesis or guideline pooled it, 44 citations in OpenAlex.
- A Systematic Review of the Associations Between Inverse Dynamics and Musculoskeletal Modeling to Investigate Joint Loading in a Clinical Environment.Frontiers in bioengineering and biotechnology · 2020Pooled it
- Alteration of Subchondral Bone Density Distribution Across the Knee Joint Before and After Anterior Cruciate Ligament Reconstruction.Orthopaedic journal of sports medicine · 2026Article
- From physical modalities to energy-responsive biomaterials: Current strategies and challenges in tendon-to-bone healing.Bioactive materials · 2026Review
- Biomechanical Analysis After Anterior Cruciate Ligament Reconstruction at the Return-to-Sport Time Point.Orthopaedic journal of sports medicine · 2025Article
- Knee joint mechanics during gait after anterior cruciate ligament reconstruction using a partial or full thickness quadriceps tendon autograft at 2 years after surgery.PM & R : the journal of injury, function, and rehabilitation · 2025Article
- Gait Asymmetry and Post-Traumatic Osteoarthritis Following Anterior Cruciate Ligament Rupture: A Preliminary Study.Biology · 2025Article
- Efficacy of a Squat Visual Biofeedback Program After ACL Reconstruction: Protocol for a Prospective, Parallel, Randomized Controlled Trial.International journal of sports physical therapy · 2025Article
- Comparison of Limb Loading Characteristics and Subjective Functional Outcomes Between Sexes After Anterior Cruciate Ligament Reconstruction.Journal of athletic training · 2024Article
- Unbalanced Medial-to-Lateral Knee Muscle Co-Contractions are Associated with Medial Tibiofemoral Underloading during Gait Three Months after Anterior Cruciate Ligament Reconstruction.Journal of biomechanics · 2024Article
- Peak knee joint moments accurately predict medial and lateral knee contact forces in patients with valgus malalignment.Scientific reports · 2023Article
- Knee joint unloading and daily physical activity associate with cartilage T2 relaxation times 1 month after ACL injury.Journal of orthopaedic research : official publication of the Orthopaedic Research Society · 2022Article
- Kinetic measurement system use in individuals following anterior cruciate ligament reconstruction: a scoping review of methodological approaches.Journal of experimental orthopaedics · 2021Article
- Patients Walking Faster After Anterior Cruciate Ligament Reconstruction Have More Gait Asymmetry.International journal of sports physical therapy · 2021Article
- Operative and nonoperative management of anterior cruciate ligament injury: Differences in gait biomechanics at 5 years.Journal of orthopaedic research : official publication of the Orthopaedic Research Society · 2020Article
- Biomechanical effects of manipulating peak vertical ground reaction force throughout gait in individuals 6-12 months after anterior cruciate ligament reconstruction.Clinical biomechanics (Bristol, Avon) · 2020Article
- Circulating microRNA let‑7e is decreased in knee osteoarthritis, accompanied by elevated apoptosis and reduced autophagy.International journal of molecular medicine · 2020Article
- Knee Loading After ACL-R Is Related to Quadriceps Strength and Knee Extension Differences Across the Continuum of Care.Orthopaedic journal of sports medicine · 2019Article
- Anterior Cruciate Ligament Research Retreat VIII Summary Statement: An Update on Injury Risk Identification and Prevention Across the Anterior Cruciate Ligament Injury Continuum, March 14-16, 2019, Greensboro, NC.Journal of athletic training · 2019Article
- Associations Between Slower Walking Speed and T1ρ Magnetic Resonance Imaging of Femoral Cartilage Following Anterior Cruciate Ligament Reconstruction.Arthritis care & research · 2018Article
- An extended OpenSim knee model for analysis of strains of connective tissues.Biomedical engineering online · 2018Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 3 institutions in 1 country.
Funding
Abstract
Anterior cruciate ligament (ACL) injury results in altered knee joint mechanics which frequently continue even after ACL reconstruction. The persistence of altered mechanical loading of the knee is of concern due to its likely role in the development of post-traumatic osteoarthritis (OA). Joint contact forces are associated with post-traumatic OA development, but evaluation of factors influencing the magnitude of contact forces after ACL injury is needed to advance current strategies aimed at preventing post-traumatic OA. Therefore, the purpose of this study was to identify predictive factors of knee joint contact forces after ACL reconstruction. Thirty athletes completed standard gait analysis with surface electromyography 6 months after ACL reconstruction. An electromyographic-driven musculoskeletal model was used to estimate joint contact forces. External knee adduction moment was a significant predictor of medial compartment contact forces in both limbs, while vertical ground reaction force and co-contraction only contributed significantly in the uninvolved limb. The large influence of the knee adduction moment on joint contact forces provides mechanistic clues to understanding the mechanical pathway of post-traumatic OA after ACL injury. Statement of Clinical Significance: This study provides critical information in improving the understanding of mechanisms influencing the development of post-traumatic OA after ACL injury. Further work is needed to identify additional driving factors of joint loading in the ACL-injured limb and develop treatment strategies to avert the deleterious consequences of post-traumatic OA. © 2016 Orthopaedic Research Society. Published by Wiley Periodicals, Inc. J Orthop Res 35:651-656, 2017.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.