Evidence map›Paper›PMID 27747631›Full record

ArticleInternational journal of implant dentistry2015

Real-time PCR analysis of fungal organisms and bacterial species at peri-implantitis sites.

Frank Schwarz, Kathrin Becker, Sebastian Rahn, Andrea Hegewald, Klaus Pfeffer, Birgit Henrich

Abstract read
In one paragraph

Article in International journal of implant dentistry, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. A systematic review on the implication of Candida in peri-implantitis.International journal of implant dentistry · 2021
    Pooled it
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  8. The Impact ofInternational journal of molecular sciences · 2024
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  14. Fungi-A Component of the Oral Microbiome Involved in Periodontal Diseases.Advances in experimental medicine and biology · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Frank SchwarzDepartment of Oral Surgery, Westdeutsche Kieferklinik, Heinrich Heine University, Moorenstraße 5, D-40225, Düsseldorf, Germany.
Kathrin BeckerDepartment of Orthodontics, Westdeutsche Kieferklinik, Heinrich Heine University, Moorenstraße 5, D-40225, Düsseldorf, Germany. kathrin.becker@med.uni-dueseldorf.de.
Sebastian RahnInstitute of Medical Microbiology and Hospital Hygiene, Heinrich Heine University, Universitätsstraße 1, D-40225, Düsseldorf, Germany.
Andrea HegewaldDepartment of Oral Surgery, Westdeutsche Kieferklinik, Heinrich Heine University, Moorenstraße 5, D-40225, Düsseldorf, Germany.
Klaus PfefferInstitute of Medical Microbiology and Hospital Hygiene, Heinrich Heine University, Universitätsstraße 1, D-40225, Düsseldorf, Germany.
Birgit HenrichInstitute of Medical Microbiology and Hospital Hygiene, Heinrich Heine University, Universitätsstraße 1, D-40225, Düsseldorf, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe potential role of fungal organisms and their co-aggregation with either periodontopathogens or opportunistic pathogens at peri-implantitis sites is unknown. The aim of the present study was to qualitatively/quantitatively analyze and correlate fungal organisms and bacterial species at peri-implantitis sites.

methodsIn a total of 29 patients, submucosal/subgingival plaque samples were collected at peri-implantitis and healthy implant sites as well as teeth with a history of periodontitis (controls). A real-time PCR assay was established for the qualification of fungal organisms and a TaqMan assay for the quantification of Porphyromonas gingivalis, Parvimonas micra, Tannerella forsythia, Mycoplasma salivarium, Veillonella parvula, and Staphylococcus aureus.

resultsFungal organisms were more frequently identified at peri-implantitis (31.6%) (i.e., Candida albicans, Candida boidinii, Penicillium spp., Rhodotorula laryngis, Paelicomyces spp., Saccharomycetes, Cladosporium cladosporioides) and healthy implant sites (40% - Candida dubliniensis, C. cladosporioides) than at selected teeth (20% - C. albicans, Fusarium solani). At implant sites, fungal organisms were significantly correlated with P. micra and T. forsythia.

conclusionsCandida spp. and other fungal organisms were frequently identified at peri-implantitis as well as healthy implant sites and co-colonized with P. micra and T. forsythia.

Indexed as

DiagnosisFungal organismsMicrobiologyPeri-implantitis

Identifiers

PMID27747631
PMCPMC5005605

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.