ReviewRheumatology and therapy2016
Juvenile Idiopathic Arthritis: Diagnosis and Treatment.
Review in Rheumatology and therapy, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05871086 (The Effect of Coenzyme Q10 Supplementation on the Clinical Outcome of Juvenile Idiopathic Arthritis Patients), which is not on this map. Cited by 111 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
The Effect of Coenzyme Q10 Supplementation on the Clinical Outcome of Juvenile Idiopathic Arthritis Patients
Who cites it
111 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Endocrine-Immune Crosstalk in Pediatric Autoimmune Diseases: A Systematic Review of the Role of Micronutrients, with Emphasis on Vitamin D.Nutrients · 2026Pooled it
- Electroacupuncture for juvenile idiopathic arthritis: clinical efficacy and its role in modulating pyroptosis and autophagy pathways.Clinical rheumatology · 2025Trial
- Prevalence and risk factors for acute kidney injury at the diagnosis of juvenile idiopathic arthritis in children and its long-term implications for kidney health.Pediatric nephrology (Berlin, Germany) · 2026Article
- Canakinumab for systemic-onset juvenile idiopathic arthritis/Still's disease-effectiveness and safety data from the BiKeR registry.EULAR rheumatology open · 2026Article
- The Role of Hydro-Kinesiotherapy After Intra-Articular Steroid Infiltration in the Management of Juvenile Idiopathic Arthritis: A Non-Randomized Observational Pre-Post Study with Parallel Groups.Journal of functional morphology and kinesiology · 2026Article
- Gait Characteristics in Children with Juvenile Idiopathic Arthritis and Secondary Scoliosis.Children (Basel, Switzerland) · 2026Article
- Dry synovitis, RF-negative: a rare entity distinct from juvenile idiopathic arthritis.Rheumatology advances in practice · 2026Article
- Reduced IgM natural autoantibody levels against heat shock proteins are associated with disease severity in juvenile idiopathic arthritis.Frontiers in immunology · 2026Article
- Evaluation of ferroptosis markers and laboratory findings in patients with juvenile idiopathic arthritis.Revista da Associacao Medica Brasileira (1992) · 2026Article
- Juvenile arthritis damage index predicts poor response to biological treatment: A prospective cohort study.World journal of clinical pediatrics · 2025Article
- Cross-Sectional and Longitudinal Immunoprofiling of Oligoarticular Juvenile Idiopathic Arthritis Reveals Different Patterns in Synovial Fluid and Plasma.Scandinavian journal of immunology · 2025Article
- Evaluating the causal effect of circulating proteome on the risk of Juvenile idiopathic arthritis: an omics pipeline study.Pediatric rheumatology online journal · 2025Article
- Diagnosing Oligoarticular Juvenile Idiopathic Arthritis in a Two-Year-Old: A Case Report.Cureus · 2025Article
- Population-Based Big Data Analysis on Disease Patterns in Patients Identified With Juvenile Idiopathic Arthritis Using National Claims Data.Journal of Korean medical science · 2025Article
- A narrative review of multidisciplinary rehabilitation in juvenile idiopathic arthritis.Clinical rheumatology · 2025Review
- Digital Interventions for Patients With Juvenile Idiopathic Arthritis: Systematic Review and Meta-Analysis.JMIR pediatrics and parenting · 2025Review
- What have we learned from long-term studies in juvenile idiopathic arthritis? - Prediction, classification, transition.Pediatric rheumatology online journal · 2025Review
- Novel Immune biomarkers for the early stratification of oligoarthritis patients at risk of developing polyarticular extension.Frontiers in immunology · 2025Article
- Efficacy of the CerveraTS Plate in an Integrated Approach to Juvenile Idiopathic Arthritis: A Long-Term Case Report.Case reports in dentistry · 2025Article
- Modifications of the Effect of Juvenile Idiopathic Arthritis (JIA) on Anxiety and Depression in Children and Adolescents: A Pseudo-longitudinal Study of 192,019 Children in the United States.Clinical practice and epidemiology in mental health : CP & EMH · 2025Article
51 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Juvenile idiopathic arthritis is a broad term that describes a clinically heterogeneous group of arthritides of unknown cause, which begin before 16 years of age. This term encompasses several disease categories, each of which has distinct presentation, clinical manifestations, and, presumably, genetic background and etiopathogenesis. Although none of the available drugs has curative potential, prognosis has greatly improved as a result of substantial progresses in disease management. The most important new development has been the introduction of the biologic medications, which constitute a valuable treatment option for patients who are resistant to conventional antirheumatic agents. Further insights into the disease pathogenesis and treatment will be provided by the continuous advances in understanding of the mechanisms related to the immune response and inflammatory process, and by the development of new drugs that are capable of selectively inhibiting single molecules or pathways.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.