Evidence map›Paper›PMID 27747467›Full record

ArticleEating and weight disorders : EWD2017

Gestational diabetes mellitus its association with obesity: a prospective cohort study.

Reihaneh Pirjani, Nooshin Shirzad, Mostafa Qorbani, Mina Phelpheli, Ensieh Nasli-Esfahani, Fatemeh Bandarian, Mahboubeh Hemmatabadi

Registry-linked trialAbstract read
PubMed Publisher
In one paragraph

Article in Eating and weight disorders : EWD, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03665974 (Lower Vitamin D Levels During Second Trimester Are Associated With Developing Gestational Diabetes Mellitus), which is not on this map. Cited by 17 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03665974 completednot on this map

Lower Vitamin D Levels During Second Trimester Are Associated With Developing Gestational Diabetes Mellitus: an Observational Cross-sectional Study

TypeobservationalSponsorHacettepe UniversityRan2013 to 2013Enrolled80ConditionsDeficiency, Vitamin D, Diabetes, Gestational
3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Imbalance of gut microbiota in gestational diabetes.BMC pregnancy and childbirth · 2024
    Trial
  4. The Emerging Role of p21 in Diabetes and Related Metabolic Disorders.International journal of molecular sciences · 2024
    Review
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  11. Opportunities for Prevention of Gestational Diabetes Before 24 Weeks of Gestation.Diabetes, metabolic syndrome and obesity : targets and therapy · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Reihaneh PirjaniDepartment of Obstetrics and Gynecology, Arash Hospital, Tehran University of Medical Sciences, Tehran, Iran.
Nooshin ShirzadEndocrinology and Metabolism Research Center, Endocrinology and Metabolism Clinical Sciences Institute, Tehran University of Medical Sciences, 5th Floor, Shariati Hospital, North Kargar Ave., Tehran, Iran. nshirzad11@gmail.com.
Mostafa QorbaniDepartment of Community Medicine, School of Medicine, Alborz University of Medical Sciences, Karaj, Iran.
Mina PhelpheliDepartment of Obstetrics and Gynecology, Arash Hospital, Tehran University of Medical Sciences, Tehran, Iran.
Ensieh Nasli-EsfahaniDiabetes Research Center, Endocrinology and Metabolism Clinical Sciences Institute, Tehran University of Medical Sciences, Tehran, Iran.
Fatemeh BandarianDiabetes Research Center, Endocrinology and Metabolism Clinical Sciences Institute, Tehran University of Medical Sciences, Tehran, Iran.
Mahboubeh HemmatabadiDepartment of Endocrinology, Vali-Asr Hospital, Imam Khomeini Complex Hospital, Tehran University of Medical Sciences, Tehran, Iran.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThe aim of this study was to investigate the association between pre-pregnancy body mass index (BMI) and gestational diabetes mellitus (GDM).

methodsThis prospective study was conducted on 256 pregnant women without diabetes referred for prenatal care in the first trimester of pregnancy to two referral University Hospitals (Shariati and Arash Hospitals) during the years 2012 and 2013. Eligible participants were selected consecutively and were followed until delivery and 6 weeks after that. Body weight and fasting plasma glucose were measured in each trimester, and BMI was calculated. Incidence of GDM was recorded, and BMI in this group was compared with those without GDM.

resultsMean age of women was 28.70 ± 5.57 years and among them, 78 women (30.5 %) developed GDM of which 21 were obese (52.5 %), 25 overweight (27.8 %), and 32 (25.4 %) were normal weight (p = 0.004). Pre-pregnancy obesity (OR 2.74, 95 % CI 1.28-5.88, p = 0.009), family history of diabetes (OR 2.01, 95 % CI 1.13-3.56, p = 0.016), and maternal age more than 30 years (OR 2.20, 95 % CI 1.25-3.88, p = 0.006) were three independent predictors for GDM, and pre-pregnancy obesity was the most potent predictor of GDM.

conclusionWomen with high BMI and obesity have a significantly higher risk for developing GDM. Pre-pregnancy obesity, family history of diabetes, and age more than 30 years are three independent risk factors for GDM.

Indexed as

Body Mass IndexAdultDiabetes, GestationalFemaleGlucose Tolerance TestHumansMaternal AgeObesityOverweightPregnancyPregnancy Trimester, FirstProspective StudiesRisk FactorsWeight GainYoung AdultBMIGestational diabetes mellitusObesity

Identifiers

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.