Evidence map›Paper›PMID 27747296›Full record

ArticlemSphere

The Spl Serine Proteases Modulate

Alexandra E Paharik, Wilmara Salgado-Pabon, David K Meyerholz, Mark J White, Patrick M Schlievert, Alexander R Horswill

Open access · goldAbstract read
In one paragraph

Article in mSphere. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 58 papers.

0numbers the graph read from it
0cells of the map it votes in
58citing papers in PubMed
4.5field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

58 citing papers in PubMed, 85 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Airway mucus in infection.Frontiers in physiology · 2026
    Review
  7. Article
  8. Article
  9. Frontiers in immunology · 2026
    Article
  10. The secreted proteasesVirulence · 2025
    Article
  11. Article
  12. Host-Microbiome Interactions in Chronic Itch.Journal of clinical medicine · 2025
    Review
  13. Article
  14. Activation of themBio · 2025
    Article
  15. Linking Virulence and Iron Limitation Response inJournal of proteome research · 2025
    Article
  16. Article
  17. Article
  18. Integrated genomic and proteomic analysis of the mouse-adaptedCurrent research in microbial sciences · 2025
    Article
  19. DNA and cell biology · 2024
    Review
  20. ThemBio · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Alexandra E PaharikDepartment of Microbiology, Carver College of Medicine, University of Iowa, Iowa City, Iowa, USA.ORCID 0000-0003-4743-0406
Wilmara Salgado-PabonDepartment of Microbiology, Carver College of Medicine, University of Iowa, Iowa City, Iowa, USA.
David K MeyerholzDepartment of Pathology, Carver College of Medicine, University of Iowa, Iowa City, Iowa, USA.
Mark J WhiteDepartment of Microbiology, Carver College of Medicine, University of Iowa, Iowa City, Iowa, USA.
Patrick M SchlievertDepartment of Microbiology, Carver College of Medicine, University of Iowa, Iowa City, Iowa, USA.
Alexander R HorswillDepartment of Microbiology, Carver College of Medicine, University of Iowa, Iowa City, Iowa, USA.
University of Iowa · US

Funding

The S. aureus biofilm lifecycleP01AI083211 · NIAID · UNIVERSITY OF NEBRASKA MEDICAL CENTER · PI BAYLES, KENNETH W. · 2009 to 2023
$32.1M
Vector Core-Core 2P30DK054759 · NIDDK · UNIVERSITY OF IOWA · PI Alejandro Antonio Pezzulo · 1998 to 2026
$30.5M
NIAID NIH HHS P01 AI083211NIDDK NIH HHS P30 DK054759
6 · The paper itself

Abstract

The Spl proteases are a group of six serine proteases that are encoded on the νSaβ pathogenicity island and are unique to

Indexed as

mucinpneumoniaproteasesSplStaphylococcus aureusvirulence factors

Identifiers

PMID27747296
PMCPMC5061998
OpenAlexW2530219859

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.