Evidence map›Paper›PMID 27747245›Full record

ArticleJournal of immunology research2016

TNF-

Jennie M Gane, Robert A Stockley, Elizabeth Sapey

Open access · goldAbstract read
In one paragraph

Article in Journal of immunology research, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 54 papers.

0numbers the graph read from it
0cells of the map it votes in
54citing papers in PubMed
2.2field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

54 citing papers in PubMed, 65 citations in OpenAlex.

  1. Single-cell analysis of microglia and monocyte dynamics uncovers distinct TNF-driven neuroimmune signatures in humans after intracerebral hemorrhage.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2026
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  18. Biomarkers for systemic lupus erythematosus: A scoping review.Immunity, inflammation and disease · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Jennie M GaneDepartment of Clinical and Experimental Medicine, University of Birmingham, Edgbaston, Birmingham, UK.ORCID 0000-0003-1629-2362
Robert A StockleyLung Investigation Unit, University Hospital Birmingham NHS Foundation Trust, Edgbaston, Birmingham, UK.
Elizabeth SapeyDepartment of Clinical and Experimental Medicine, University of Birmingham, Edgbaston, Birmingham, UK.ORCID 0000-0003-3454-5482
University of Birmingham · GBUniversity Hospitals Birmingham NHS Foundation Trust · GB

Funding

Medical Research Council MR/L008335/1
6 · The paper itself

Abstract

Selective TNFR1 blockade in inflammatory diseases is emerging as a clinical strategy. We studied the roles of the two TNF-

Indexed as

Autocrine CommunicationAdultCell MembraneCells, CulturedCytokinesFemaleGene ExpressionHumansInflammationInflammation MediatorsMaleMiddle AgedMonocytesReceptors, Tumor Necrosis FactorReceptors, Tumor Necrosis Factor, Type IReceptors, Tumor Necrosis Factor, Type IICytokinesInflammation MediatorsReceptors, Tumor Necrosis FactorReceptors, Tumor Necrosis Factor, Type IReceptors, Tumor Necrosis Factor, Type IITumor Necrosis Factor-alpha

Identifiers

PMID27747245
PMCPMC5055993
OpenAlexW2522140636

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.