Evidence map›Paper›PMID 27747211›Full record

ArticleFrontiers in bioengineering and biotechnology2016

Subfailure Overstretch Injury Leads to Reversible Functional Impairment and Purinergic P2X7 Receptor Activation in Intact Vascular Tissue.

Weifeng Luo, Christy M Guth, Olukemi Jolayemi, Craig L Duvall, Colleen Marie Brophy, Joyce Cheung-Flynn

Open access · goldAbstract read
In one paragraph

Article in Frontiers in bioengineering and biotechnology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.1field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Article
  3. A cell permeant phosphopeptide mimetic of Niban inhibits p38 MAPK and restores endothelial function after injury.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2020
    Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Weifeng LuoDepartment of Surgery, Vanderbilt University , Nashville, TN , USA.
Christy M GuthDepartment of Surgery, Vanderbilt University , Nashville, TN , USA.
Olukemi JolayemiDepartment of Surgery, Vanderbilt University , Nashville, TN , USA.
Craig L DuvallDepartment of Biomedical Engineering, Vanderbilt University , Nashville, TN , USA.
Colleen Marie BrophyDepartment of Surgery, Vanderbilt University, Nashville, TN, USA; VA Tennessee Valley Healthcare System, Nashville, TN, USA.
Joyce Cheung-FlynnDepartment of Surgery, Vanderbilt University , Nashville, TN , USA.
Vanderbilt University · US

Funding

PREVENTION OF VEIN GRAFT SPASMR01HL070715 · NHLBI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI BROPHY, COLLEEN M · 2003 to 2021
$7.2M
Methods To Reduce Vein Harvest InjuryR01HL105731 · NHLBI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI CHEUNG-FLYNN, JOYCE · 2012 to 2015
$1.4M
NHLBI NIH HHS R01 HL070715NHLBI NIH HHS R01 HL105731
6 · The paper itself

Abstract

Vascular stretch injury is associated with blunt trauma, vascular surgical procedures, and harvest of human saphenous vein for use in vascular bypass grafting. A model of subfailure overstretch in rat abdominal aorta was developed to characterize surgical vascular stretch injury. Longitudinal stretch of rat aorta was characterized

Indexed as

mechanical stretchP2X7Rrat modelsubfailure overstretchvascular injuryvasomotor function

Identifiers

PMID27747211
PMCPMC5040722
OpenAlexW2527467600

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.