ArticleResearch and reports in nuclear medicine2015
Double agents and secret agents: the emerging fields of exogenous chemical exchange saturation transfer and T
Article in Research and reports in nuclear medicine, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
12 citing papers in PubMed, 13 citations in OpenAlex.
- Probing nitric oxide signaling using molecular MRI.Free radical biology & medicine · 2022Review
- Repurposing Clinical Agents for Chemical Exchange Saturation Transfer Magnetic Resonance Imaging: Current Status and Future Perspectives.Pharmaceuticals (Basel, Switzerland) · 2020Review
- Binding site exchange kinetics revealed through efficient spin-spin dephasing of hyperpolarizedChemical science · 2020Article
- Probing Reversible Guest Binding with HyperpolarizedMolecules (Basel, Switzerland) · 2020Review
- Sugar-based biopolymers as novel imaging agents for molecular magnetic resonance imaging.Wiley interdisciplinary reviews. Nanomedicine and nanobiotechnology · 2019Review
- Triazoles as TChemistry (Weinheim an der Bergstrasse, Germany) · 2018Article
- Characterization of D-maltose as a TMagnetic resonance in medicine · 2018Article
- Phenols as Diamagnetic TChemistry (Weinheim an der Bergstrasse, Germany) · 2018Article
- Detecting in vivo urokinase plasminogen activator activity with a catalyCEST MRI contrast agent.NMR in biomedicine · 2017Article
- Detection of DT-diaphorase Enzyme with a ParaCEST MRI Contrast Agent.Chemistry (Weinheim an der Bergstrasse, Germany) · 2017Article
- A biomarker-responsive TMagnetic resonance in medicine · 2017Article
- Detection of Alkaline Phosphatase Enzyme Activity with a CatalyCEST MRI Biosensor.ACS sensors · 2016Article
Corrections and comments
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Authors and funding
2 authors at 2 institutions in 1 country.
Funding
Abstract
Two relatively new types of exogenous magnetic resonance imaging contrast agents may provide greater impact for molecular imaging by providing greater specificity for detecting molecular imaging biomarkers. Exogenous chemical exchange saturation transfer (CEST) agents rely on the selective saturation of the magnetization of a proton on an agent, followed by chemical exchange of a proton from the agent to water. The selective detection of a biomarker-responsive CEST signal and an unresponsive CEST signal, followed by the ratiometric comparison of these signals, can improve biomarker specificity. We refer to this improvement as a "double-agent" approach to molecular imaging. Exogenous T
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.