Evidence map›Paper›PMID 27747143›Full record

ArticleMessenger (Los Angeles, Calif. : Print)2015

Calcium Signalling Triggered by NAADP in T Cells Determines Cell Shape and Motility During Immune Synapse Formation.

Merle Nebel, Bo Zhang, Francesca Odoardi, Alexander Flügel, Barry V L Potter, Andreas H Guse

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Messenger (Los Angeles, Calif. : Print), 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.1field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 8 citations in OpenAlex.

  1. Imaging BiTE-Mediated Activation of Primary Human CD8Methods in molecular biology (Clifton, N.J.) · 2025
    Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Merle NebelThe Calcium Signalling Group, Department of Biochemistry and Signal Transduction, University Medical Centre Hamburg-Eppendorf, Martinistrasse 52, 20246 Hamburg, Germany.
Bo ZhangWolfson Laboratory of Medicinal Chemistry, Department of Pharmacy and Pharmacology, University of Bath, Claverton Down, Bath BA2 7AY, UK.
Francesca OdoardiInstitute for Multiple Sclerosis Research, Department of Neuroimmunology, Gemeinnützige Hertie-Stiftung and University Medical Centre Göttingen, 37073 Göttingen, Germany.
Alexander FlügelInstitute for Multiple Sclerosis Research, Department of Neuroimmunology, Gemeinnützige Hertie-Stiftung and University Medical Centre Göttingen, 37073 Göttingen, Germany.
Barry V L PotterWolfson Laboratory of Medicinal Chemistry, Department of Pharmacy and Pharmacology, University of Bath, Claverton Down, Bath BA2 7AY, UK.
Andreas H GuseThe Calcium Signalling Group, Department of Biochemistry and Signal Transduction, University Medical Centre Hamburg-Eppendorf, Martinistrasse 52, 20246 Hamburg, Germany; Department of Biochemistry and Molecular Cell Biology, University Medical Centre Hamburg-Eppendorf, Martinistrasse 52, 20246 Hamburg, Germany.
University of Bath · GBUniversität Hamburg · DEUniversity Medical Center Hamburg-Eppendorf · DE

Funding

Wellcome Trust 068065
6 · The paper itself

Abstract

Nicotinic acid adenine dinucleotide phosphate (NAADP) has been implicated as an initial Ca

Indexed as

Ca2+ SignallingCytoskeletonLive Cell ImagingNAADPT Cell Activation

Identifiers

PMID27747143
PMCPMC5065091
OpenAlexW2341667425

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.