Evidence map›Paper›PMID 27747027›Full record

ReviewJournal of thoracic disease2016

Developing miRNA therapeutics for cardiac repair in ischemic heart disease.

Kai Zhu, Dingqian Liu, Hao Lai, Jun Li, Chunsheng Wang

Open access · hybridAbstract readReview
In one paragraph

Review in Journal of thoracic disease, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
1.7field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 32 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Article
  5. The Diverse Manifestations of Regeneration and Why We Need to Study Them.Cold Spring Harbor perspectives in biology · 2021
    Article
  6. Review
  7. Observational
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Review
  16. Article
  17. Article
  18. Targeting miRNA for Therapy of Juvenile and Adult Diabetic Cardiomyopathy.Advances in experimental medicine and biology · 2018
    Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Kai ZhuDepartment of Cardiac Surgery, Zhongshan Hospital, Fudan University, Shanghai 200032, China;; Shanghai Institute of Cardiovascular Disease, Shanghai 200032, China.
Dingqian LiuDepartment of Cardiac Surgery, Zhongshan Hospital, Fudan University, Shanghai 200032, China;; Shanghai Institute of Cardiovascular Disease, Shanghai 200032, China.
Hao LaiDepartment of Cardiac Surgery, Zhongshan Hospital, Fudan University, Shanghai 200032, China;; Shanghai Institute of Cardiovascular Disease, Shanghai 200032, China.
Jun LiDepartment of Cardiac Surgery, Zhongshan Hospital, Fudan University, Shanghai 200032, China;; Shanghai Institute of Cardiovascular Disease, Shanghai 200032, China.
Chunsheng WangDepartment of Cardiac Surgery, Zhongshan Hospital, Fudan University, Shanghai 200032, China;; Shanghai Institute of Cardiovascular Disease, Shanghai 200032, China.
Zhongshan Hospital · CNFudan University · CNShanghai Institute of Hematology · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

MicroRNAs (miRNAs) families have been found to be powerful regulators in a wide variety of diseases, which enables the possible use of miRNAs in therapeutic strategies for cardiac repair after ischemic heart disease. This review provides some general insights into miRNAs modulation for development of current molecular and cellular therapeutics in cardiac repair, including endogenous regeneration, endogenous repair, stem cells transplantation, and reprogramming. We also review the delivery strategies for miRNAs modulation, and briefly summarize the current bench and clinical efforts that are being made to explore miRNAs as the future therapeutic target.

Indexed as

cardiac repairMicroRNAs (miRNAs)modulationregenerationstem cells

Identifiers

PMID27747027
PMCPMC5059336
OpenAlexW2513538126

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.