Evidence map›Paper›PMID 27746915›Full record

ArticleJournal of materials chemistry. B2016

Fortified interpenetrating polymers - bacteria resistant coatings for medical devices.

Seshasailam Venkateswaran, Orlando David Henrique Dos Santos, Emma Scholefield, Annamaria Lilienkampf, Peter J Gwynne, David G Swann, Kevin Dhaliwal, Maurice P Gallagher, Mark Bradley

Open access · hybridAbstract read
In one paragraph

Article in Journal of materials chemistry. B, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.1field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 18 citations in OpenAlex.

  1. Review
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  3. Review
  4. Article
  5. Natural compounds in the fight againstFrontiers in pharmacology · 2024
    Review
  6. Review
  7. Review
  8. Antimicrobial Coating: Tracheal Tube Application.International journal of nanomedicine · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 3 countries.

Seshasailam VenkateswaranEaStCHEM School of Chemistry , University of Edinburgh , King's Buildings , West Mains Road , Edinburgh , EH9 3FJ , UK . Email: mark.bradley@ed.ac.uk.
Orlando David Henrique Dos SantosLaboratório de Fitotecnologia , Departamento de Farmácia , Escola de Farmácia , Universidade Federal de Ouro Preto , Ouro Preto , Minas Gerais 35400-000 , Brazil.
Emma ScholefieldMRC Centre for Inflammation Research , The Queens Medical Research Institute , University of Edinburgh , 47 Little France Crescent , Edinburgh EH16 4TJ , UK.
Annamaria LilienkampfEaStCHEM School of Chemistry , University of Edinburgh , King's Buildings , West Mains Road , Edinburgh , EH9 3FJ , UK . Email: mark.bradley@ed.ac.uk.
Peter J GwynneSchool of Biological Sciences , University of Edinburgh, King's Buildings , West Mains Road , Edinburgh , EH9 3JF , UK.
David G SwannCritical Care , NHS Lothian , Royal Infirmary of Edinburgh , 51 Little France Crescent , Edinburgh , EH16 4SA , UK.
Kevin DhaliwalMRC Centre for Inflammation Research , The Queens Medical Research Institute , University of Edinburgh , 47 Little France Crescent , Edinburgh EH16 4TJ , UK.
Maurice P GallagherSchool of Biological Sciences , University of Edinburgh, King's Buildings , West Mains Road , Edinburgh , EH9 3JF , UK.
Mark BradleyEaStCHEM School of Chemistry , University of Edinburgh , King's Buildings , West Mains Road , Edinburgh , EH9 3FJ , UK . Email: mark.bradley@ed.ac.uk.
University of Edinburgh · GBCentre for Inflammation Research · GBThe King's College · USNHS Lothian · GBUniversidade Federal de Ouro Preto · BR

Funding

Medical Research Council G0901697
6 · The paper itself

Abstract

Infections arising from contaminated medical devices are a serious global issue, contributing to antibiotic resistance and imposing significant strain on healthcare systems. Since the majority of medical device-associated infections are biofilm related, efforts are being made to generate either bacteria-repellent or antibacterial coatings aimed at preventing bacterial colonisation. Here, we utilise a nanocapsule mediated slow release of a natural antimicrobial to improve the performance of a bacteria repellent polymer coating. Poly(lauryl acrylate) nanocapsules containing eugenol (4-allyl-2-methoxyphenol) were prepared and entrapped within a interpenetrating network designed to repel bacteria. When coated on a catheter and an endotracheal tube, this hemocompatible system allowed slow-release of eugenol, resulting in notable reduction in surface-bound

Identifiers

PMID27746915
PMCPMC5038341
OpenAlexW2484599603

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.