Evidence map›Paper›PMID 27746909›Full record

ArticleF1000Research2016

Analysis of morphine responses in mice reveals a QTL on Chromosome 7.

Wim E Crusio, Esha Dhawan, Elissa J Chesler, Anna Delprato

Open access · goldAbstract read
In one paragraph

Article in F1000Research, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.7field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Systems Genetic Analysis in GeneNetwork.org.Current protocols in neuroscience · 2017
    Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 2 countries.

Wim E CrusioInstitut de Neurosciences Cognitives et Intégratives d'Aquitaine, UMR 5287, University of Bordeaux, Pessac cedex, France; Institut de Neurosciences Cognitives et Intégratives d'Aquitaine, UMR 5287, CNRS, Pessac, France.
Esha DhawanLambert High School, Suwanee, USA; BioScience Project, Wakefield, USA.
Elissa J CheslerJackson Laboratory, Bar Harbor, USA.
Anna DelpratoBioScience Project, Wakefield, USA.
Jackson Laboratory · USUniversité de Bordeaux · FR

Funding

Discovery of Addiction-Related Genes with Advanced Mouse ResourcesR01DA037927 · NIDA · JACKSON LABORATORY · PI CHESLER, ELISSA J · 2015 to 2025
$8.1M
Data Structures, Algorithms and Tools for Ontological DiscoveryR01AA018776 · NIAAA · JACKSON LABORATORY · PI CHESLER, ELISSA J · 2010 to 2019
$3.9M
NIAAA NIH HHS R01 AA018776NIDA NIH HHS R01 DA037927
6 · The paper itself

Abstract

In this study we identified a quantitative trait locus (QTL) on mouse Chromosome 7 associated with locomotor activity and rearing post morphine treatment. This QTL was revealed after correcting for the effects of another QTL peak on Chromosome 10 using composite interval mapping. The positional candidate genes are

Indexed as

Locomotor activityOpioidsQTL analysisReward pathway

Identifiers

PMID27746909
PMCPMC5043443
OpenAlexW2518124041

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.