Evidence map›Paper›PMID 27746862›Full record

ArticleIranian journal of basic medical sciences2016

Hyperbaric environment up-regulates CD15s expression on leukocytes, down-regulates CD77 expression on renal cells and up-regulates CD34 expression on pulmonary and cardiac cells in rat.

Danka Đevenica, Anita Markotić, Nikolina Režić-Mužinić, Igor Jelaska, Tatijana Zemunik, Hrvoje Delić, Vedrana Čikeš Čulić

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Article in Iranian journal of basic medical sciences, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 93% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Danka ĐevenicaPostgraduate Student at University of Split School of Medicine, Split, Croatia.
Anita MarkotićDepartment of Medical Chemistry and Biochemistry, University of Split School of Medicine, Split, Croatia.
Nikolina Režić-MužinićDepartment of Medical Chemistry and Biochemistry, University of Split School of Medicine, Split, Croatia.
Igor JelaskaFaculty of Kinesiology, University of Split, Split, Croatia.
Tatijana ZemunikDepartment of Medical Biology, University of Split School of Medicine, Split, Croatia.
Hrvoje DelićDepartment of Medical Chemistry and Biochemistry, University of Split School of Medicine, Split, Croatia.
Vedrana Čikeš ČulićDepartment of Medical Chemistry and Biochemistry, University of Split School of Medicine, Split, Croatia.
University of Split · HR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesThe aim of this study was to estimate effects of hyperbaric (HB) treatment by determination of CD15s and CD11b leukocyte proinflammatory markers expression. In addition, this study describes changes in CD77 and CD34 expression on rat endothelial cells in renal, pulmonary and cardiac tissue following exposure to hyperbaric pressure. MATERIALS AND

methodsExpression of CD11b and CD15s on leukocytes, as well as CD77 and CD34 expression on endothelial cells in cell suspensions of renal, pulmonary and cardiac tissue in rats after hyperbaric treatment and in control rats were determined by flow cytometry.

resultsHyperbaric treatment significantly increased percentage of leukocytes expressing CD15s+CD11b- (from 1.71±1.11 to 23.42±2.85,

conclusionThe current findings of increased percentage of leukocytes expressing endothelial selectin ligand CD15s after hyperbaric treatment, point its role in endothelial damage prevention. We found out a significantly increase in percentage of CD34+ cardiac cells as well as CD34+ pulmonary cells in rats after HB treatment which could be a part of repair mechanism of injured endothelium caused by hyperoxia.

Indexed as

CD15s(sialyl Lexis X antigen)CD34 antigenCD77(globotriaosylceramide)Environment

Identifiers

PMID27746862
PMCPMC5048116
OpenAlexW2509599508

What OpenQuestion holds

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LicenceCC BY-NC-SA
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.