Evidence map›Paper›PMID 27746806›Full record

ArticleFrontiers in plant science2016

Exploring the Metabolic Stability of Engineered Hairy Roots after 16 Years Maintenance.

Suvi T Häkkinen, Elisabeth Moyano, Rosa M Cusidó, Kirsi-Marja Oksman-Caldentey

Open access · goldAbstract read
In one paragraph

Article in Frontiers in plant science, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
2.4field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 64 citations in OpenAlex.

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  7. Pharmaceuticals (Basel, Switzerland) · 2023
    Article
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  17. Plants (Basel, Switzerland) · 2021
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 2 countries.

Suvi T HäkkinenVTT Technical Research Centre of Finland Ltd. Espoo, Finland.
Elisabeth MoyanoDepartament de Ciències Experimentals i de la Salut, Universitat Pompeu Fabra Barcelona, Spain.
Rosa M CusidóSecció de Fisiologia Vegetal, Facultat de Farmàcia, Universitat de Barcelona Barcelona, Spain.
Kirsi-Marja Oksman-CaldenteyVTT Technical Research Centre of Finland Ltd. Espoo, Finland.
VTT Technical Research Centre of Finland · FIPompeu Fabra University · ESUniversitat de Barcelona · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Plants remain a major source of new drugs, leads and fine chemicals. Cell cultures deriving from plants offer a fascinating tool to study plant metabolic pathways and offer large scale production systems for valuable compounds - commercial examples include compounds such as paclitaxel. The major constraint with undifferentiated cell cultures is that they are generally considered to be genetically unstable and cultured cells tend to produce low yields of secondary metabolites especially over time. Hairy roots, a tumor tissue caused by infection of

Indexed as

cryopreservationhairy rootshyoscyamine 6β-hydroxylaseplant cell culturescopolaminestability

Identifiers

PMID27746806
PMCPMC5044514
OpenAlexW2526544758

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.