Evidence map›Paper›PMID 27746783›Full record

ArticleFrontiers in immunology2016

Anti-Lipid IgG Antibodies Are Produced

Carlos Wong-Baeza, Albany Reséndiz-Mora, Luis Donis-Maturano, Isabel Wong-Baeza, Luz Zárate-Neira, Juan Carlos Yam-Puc, Juana Calderón-Amador, Yolanda Medina, Carlos Wong, Isabel Baeza and 1 more

Erratum issuedOpen access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
2.7field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 23 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Proteomic Analysis of Membrane Blebs ofFrontiers in microbiology · 2019
    Article
  9. CD1: A Singed Cat of the Three Antigen Presentation Systems.Archivum immunologiae et therapiae experimentalis · 2017
    Review
  10. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 2 countries.

Carlos Wong-BaezaDepartment of Cell Biology, Center for Research and Advanced Studies, CINVESTAV-IPN, National Polytechnic Institute, Mexico City, Mexico; Laboratorio de Biomembranas, Departamento de Bioquímica, Escuela Nacional de Ciencias Biológicas (ENCB), IPN, Ciudad de México, México.
Albany Reséndiz-MoraLaboratorio de Biomembranas, Departamento de Bioquímica, Escuela Nacional de Ciencias Biológicas (ENCB), IPN , Ciudad de México , México.
Luis Donis-MaturanoDepartment of Cell Biology, Center for Research and Advanced Studies, CINVESTAV-IPN, National Polytechnic Institute , Mexico City , Mexico.
Isabel Wong-BaezaLaboratorio de Inmunología Molecular II, Departamento de Inmunología, ENCB, IPN , Ciudad de México , México.
Luz Zárate-NeiraLaboratorio de Biomembranas, Departamento de Bioquímica, Escuela Nacional de Ciencias Biológicas (ENCB), IPN , Ciudad de México , México.
Juan Carlos Yam-PucDepartment of Cell Biology, Center for Research and Advanced Studies, CINVESTAV-IPN, National Polytechnic Institute , Mexico City , Mexico.
Juana Calderón-AmadorDepartment of Cell Biology, Center for Research and Advanced Studies, CINVESTAV-IPN, National Polytechnic Institute , Mexico City , Mexico.
Yolanda MedinaLaboratory of monoclonal antibodies, Institute of Epidemiological Diagnosis and Reference , Mexico City , Mexico.
Carlos WongLaboratorio de Biomembranas, Departamento de Bioquímica, Escuela Nacional de Ciencias Biológicas (ENCB), IPN , Ciudad de México , México.
Isabel BaezaLaboratorio de Biomembranas, Departamento de Bioquímica, Escuela Nacional de Ciencias Biológicas (ENCB), IPN , Ciudad de México , México.
Leopoldo Flores-RomoDepartment of Cell Biology, Center for Research and Advanced Studies, CINVESTAV-IPN, National Polytechnic Institute , Mexico City , Mexico.
Instituto Politécnico Nacional · MXCentro de Investigación y de Estudios Avanzados del Instituto Politécnico Nacional · MXInstituto Nacional de Perinatología · MXLimnological Institute · RU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Anti-lipid IgG antibodies are produced in some mycobacterial infections and in certain autoimmune diseases [such as anti-phospholipid syndrome, systemic lupus erythematosus (SLE)]. However, few studies have addressed the B cell responses underlying the production of these immunoglobulins. Anti-lipid IgG antibodies are consistently found in a murine model resembling human lupus induced by chlorpromazine-stabilized non-bilayer phospholipid arrangements (NPA). NPA are transitory lipid associations found in the membranes of most cells; when NPA are stabilized they can become immunogenic and induce specific IgG antibodies, which appear to be involved in the development of the mouse model of lupus. Of note, anti-NPA antibodies are also detected in patients with SLE and leprosy. We used this model of lupus to investigate

Indexed as

antigen-specific cellsanti-lipid IgG antibodiesautoimmune diseasenon-bilayer phospholipid arrangementssystemic lupus erythematosus

Identifiers

PMID27746783
PMCPMC5040728
OpenAlexW2527217890

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.