Evidence map›Paper›PMID 27746740›Full record

ArticleFrontiers in physiology2016

Moderate Hyperbilirubinemia Alters Neonatal Cardiorespiratory Control and Induces Inflammation in the Nucleus Tractus Solitarius.

Marie-Laure Specq, Mélisande Bourgoin-Heck, Nathalie Samson, François Corbin, Christian Gestreau, Maxime Richer, Hazim Kadhim, Jean-Paul Praud

Open access · goldAbstract read
In one paragraph

Article in Frontiers in physiology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.3field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 3 countries.

Marie-Laure SpecqNeonatal Respiratory Research Unit, Departments of Pediatrics and Pharmacology - Physiology, Université de Sherbrooke Sherbrooke, QC, Canada.
Mélisande Bourgoin-HeckNeonatal Respiratory Research Unit, Departments of Pediatrics and Pharmacology - Physiology, Université de Sherbrooke Sherbrooke, QC, Canada.
Nathalie SamsonNeonatal Respiratory Research Unit, Departments of Pediatrics and Pharmacology - Physiology, Université de Sherbrooke Sherbrooke, QC, Canada.
François CorbinDepartment of Biochemistry, Université de Sherbrooke Sherbrooke, QC, Canada.
Christian GestreauAix-Marseille University, CNRS, CRN2M Marseille, France.
Maxime RicherDepartment of Pathology, Université de Sherbrooke Sherbrooke, QC, Canada.
Hazim KadhimNeuropathology Unit and Reference Center for Neuro-Muscular Pathology, Brugmann University Hospital and Childrens' Hospital (CHU Brugmann - HUDERF), Université Libre de Bruxelles Brussels, Belgium.
Jean-Paul PraudNeonatal Respiratory Research Unit, Departments of Pediatrics and Pharmacology - Physiology, Université de Sherbrooke Sherbrooke, QC, Canada.
Université de Sherbrooke · CACentre de Recherche en Neurobiologie - Neurophysiologie de Marseille · FRCentre Hospitalier Universitaire Brugmann · BE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hyperbilirubinemia (HB) occurs in 90% of preterm newborns. Moderate HB can induce acute neurological disorders while severe HB has been linked to a higher incidence of apneas of prematurity. The present study aimed to test the hypothesis that even moderate HB disrupts cardiorespiratory control in preterm lambs. Two groups of preterm lambs (born 14 days prior to term), namely control (

Indexed as

brainhyperbilirubinemiahypoxianucleus tractus solitariuspathophysiologyprematuritypulmonary and laryngeal chemoreflexes

Identifiers

PMID27746740
PMCPMC5043013
OpenAlexW2526908147

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.