Evidence map›Paper›PMID 27746581›Full record

ArticleProceedings of SPIE--the International Society for Optical Engineering2016

Diffusion-sensitive optical coherence tomography for real-time monitoring of mucus thinning treatments.

Richard L Blackmon, Silvia M Kreda, Patrick R Sears, Lawrence E Ostrowski, David B Hill, Brian S Chapman, Joseph B Tracy, Amy L Oldenburg

Open access · greenAbstract read
In one paragraph

Article in Proceedings of SPIE--the International Society for Optical Engineering, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.8field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Diffusion-Based 3D Bioprinting Strategies.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2024
    Review
  3. Article
  4. Article
  5. TheThe European respiratory journal · 2018
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Richard L BlackmonDepartment of Physics and Astronomy, University of North Carolina at Chapel Hill, NC 27599.
Silvia M KredaMarsico Lung Institute/Cystic Fibrosis Research and Treatment Center, University of North Carolina at Chapel Hill, NC 27599.
Patrick R SearsMarsico Lung Institute/Cystic Fibrosis Research and Treatment Center, University of North Carolina at Chapel Hill, NC 27599.
Lawrence E OstrowskiMarsico Lung Institute/Cystic Fibrosis Research and Treatment Center, University of North Carolina at Chapel Hill, NC 27599.
David B HillDepartment of Physics and Astronomy, University of North Carolina at Chapel Hill, NC 27599; Marsico Lung Institute/Cystic Fibrosis Research and Treatment Center, University of North Carolina at Chapel Hill, NC 27599.
Brian S ChapmanDepartment of Material Science & Engineering, North Carolina State University, Raleigh, NC 27695.
Joseph B TracyDepartment of Material Science & Engineering, North Carolina State University, Raleigh, NC 27695.
Amy L OldenburgDepartment of Physics and Astronomy, University of North Carolina at Chapel Hill, NC 27599.
University of North Carolina at Chapel Hill · USNorth Carolina State University · US

Funding

UNC CLINICAL AND TRANSLATIONAL SCIENCE AWARD: BPCAUL1RR025747 · NCRR · UNIV OF NORTH CAROLINA CHAPEL HILL · PI RUNGE, MARSCHALL S. · 2008 to 2011
$44.6M
UNC-CH CENTER FOR ENVIRONMENTAL HEALTH &SUSCEPTIBILITYP30ES010126 · NIEHS · UNIV OF NORTH CAROLINA CHAPEL HILL · PI Melissa A. Troester · 2001 to 2026
$36.3M
Vector CoreP30DK065988 · NIDDK · UNIV OF NORTH CAROLINA CHAPEL HILL · PI Richard Charles Boucher, Martina Gentzsch · 2004 to 2026
$26.5M
The Biophysics of Mucus Hydration and Adhesion/CohesionP01HL108808 · NHLBI · UNIV OF NORTH CAROLINA CHAPEL HILL · PI PEDEN, DAVID B. · 2012 to 2021
$23.9M
The Role of Airway Surface Liquid Nucleotides/Nucleosides in Volume HomeostasisP01HL034322 · NHLBI · UNIV OF NORTH CAROLINA CHAPEL HILL · PI O'NEAL, WANDA K · 1986 to 2011
$22.1M
Synthesis of Effective and Safe Mucolytics for Pulmonary DiseaseUH3HL123645 · NHLBI · UNIV OF NORTH CAROLINA CHAPEL HILL · PI BOUCHER, RICHARD CHARLES · 2016 to 2018
$4.6M
Functional Studies of Novel Genes Mutated in Primary Ciliary Dyskinesia II: Genotype to PhenotypeR01HL117836 · NHLBI · UNIV OF NORTH CAROLINA CHAPEL HILL · PI OSTROWSKI, LAWRENCE E · 2013 to 2023
$4.4M
Synthesis of Effective and Safe Mucolytics for Pulmonary DiseaseUH2HL123645 · NHLBI · UNIV OF NORTH CAROLINA CHAPEL HILL · PI BOUCHER, RICHARD CHARLES · 2014 to 2015
$2.9M
Anatomic optical coherence tomography for quantitative bronchoscopyR01HL123557 · NHLBI · UNIV OF NORTH CAROLINA CHAPEL HILL · PI OLDENBURG, AMY L, ZDANSKI, CARLTON J · 2015 to 2017
$1.9M
Imaging nanophysical properties of actively transporting bronchial mucusR21HL130901 · NHLBI · UNIV OF NORTH CAROLINA CHAPEL HILL · PI OLDENBURG, AMY L · 2016 to 2017
$418k
Development of a method for in situ nanorheology of human airway mucusR21HL111968 · NHLBI · UNIV OF NORTH CAROLINA CHAPEL HILL · PI OLDENBURG, AMY L · 2012 to 2013
$392k
NCRR NIH HHS UL1 RR025747NHLBI NIH HHS P01 HL034322NHLBI NIH HHS P01 HL108808NHLBI NIH HHS R01 HL117836NHLBI NIH HHS R01 HL123557NHLBI NIH HHS R21 HL111968NHLBI NIH HHS R21 HL130901NHLBI NIH HHS UH2 HL123645NHLBI NIH HHS UH3 HL123645NIDDK NIH HHS P30 DK065988NIEHS NIH HHS P30 ES010126
6 · The paper itself

Abstract

Mucus hydration (wt%) has become an increasingly useful metric in real-time assessment of respiratory health in diseases like cystic fibrosis and COPD, with higher wt% indicative of diseased states. However, available

Indexed as

diffusiondiffusion sensitive optical coherence tomographygold nanorodspolarization sensitive optical coherence tomography

Identifiers

PMID27746581
PMCPMC5061133
OpenAlexW2299640798

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.