Evidence map›Paper›PMID 27746280›Full record

ArticleThe Journal of urology2017

Utility Estimation for Pediatric Vesicoureteral Reflux: Methodological Considerations Using an Online Survey Platform.

Rohit Tejwani, Hsin-Hsiao S Wang, Jessica C Lloyd, Paul J Kokorowski, Caleb P Nelson, Jonathan C Routh

Abstract read
In one paragraph

Article in The Journal of urology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Crowdsourcing utility estimation for spina bifida in the general population.Journal of pediatric rehabilitation medicine · 2017
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors.

Rohit TejwaniDivision of Urologic Surgery, Duke University Medical Center, Durham, North Carolina.
Hsin-Hsiao S WangDivision of Urologic Surgery, Duke University Medical Center, Durham, North Carolina.
Jessica C LloydDivision of Urologic Surgery, Duke University Medical Center, Durham, North Carolina.
Paul J KokorowskiDivision of Pediatric Urology, Children's Hospital Los Angeles, Los Angeles, California.
Caleb P NelsonDepartment of Urology, Boston Children's Hospital, Boston, Massachusetts.
Jonathan C RouthDivision of Urologic Surgery, Duke University Medical Center, Durham, North Carolina. Electronic address: Jonathan.Routh@duke.edu.

Funding

Clinical Outcomes for Siblings of Children with Vesico-Ureteral RefluxK23DK088943 · NIDDK · BOSTON CHILDREN'S HOSPITAL · PI NELSON, CALEB PENNELL · 2010 to 2014
$892k
Comparative Effectiveness of Vesicoureteral Reflux Treatments in ChildrenK08DK100534 · NIDDK · DUKE UNIVERSITY · PI ROUTH, JONATHAN C · 2014 to 2018
$671k
NIDDK NIH HHS K08 DK100534NIDDK NIH HHS K23 DK088943NIDDK NIH HHS L40 DK084781
6 · The paper itself

Abstract

purposeThe advent of online task distribution has opened a new avenue for efficiently gathering community perspectives needed for utility estimation. Methodological consensus for estimating pediatric utilities is lacking, with disagreement over whom to sample, what perspective to use (patient vs parent) and whether instrument induced anchoring bias is significant. We evaluated what methodological factors potentially impact utility estimates for vesicoureteral reflux. MATERIALS AND

methodsCross-sectional surveys using a time trade-off instrument were conducted via the Amazon Mechanical Turk® (https://www.mturk.com) online interface. Respondents were randomized to answer questions from child, parent or dyad perspectives on the utility of a vesicoureteral reflux health state and 1 of 3 "warm-up" scenarios (paralysis, common cold, none) before a vesicoureteral reflux scenario. Utility estimates and potential predictors were fitted to a generalized linear model to determine what factors most impacted utilities.

resultsA total of 1,627 responses were obtained. Mean respondent age was 34.9 years. Of the respondents 48% were female, 38% were married and 44% had children. Utility values were uninfluenced by child/personal vesicoureteral reflux/urinary tract infection history, income or race. Utilities were affected by perspective and were higher in the child group (34% lower in parent vs child, p <0.001, and 13% lower in dyad vs child, p <0.001). Vesicoureteral reflux utility was not significantly affected by the presence or type of time trade-off warm-up scenario (p = 0.17).

conclusionsTime trade-off perspective affects utilities when estimated via an online interface. However, utilities are unaffected by the presence, type or absence of warm-up scenarios. These findings could have significant methodological implications for future utility elicitations regarding other pediatric conditions.

Indexed as

Cost-Benefit AnalysisInternetVesico-Ureteral RefluxAdultChildCross-Sectional StudiesFemaleHumansMaleSurveys and Questionnairescost-benefit analysispediatricsvesico-ureteral reflux

Identifiers

PMID27746280
PMCPMC5315661

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.