Evidence map›Paper›PMID 27744641›Full record

ArticleThe journal of physiological sciences : JPS2017

Somatosensory regulation of serotonin release in the central nucleus of the amygdala is mediated via corticotropin releasing factor and gamma-aminobutyric acid in the dorsal raphe nucleus.

Ryota Tokunaga, Rie Shimoju, Hideshi Shibata, Mieko Kurosawa

Open access · goldAbstract read
In one paragraph

Article in The journal of physiological sciences : JPS, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.1field-weighted citation impact, top 51% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Ryota TokunagaCenter for Medical Science, International University of Health and Welfare, 2600-1 Kitakanemaru, Otawara, Tochigi, 324-8501, Japan.
Rie ShimojuDivision of Physical Therapy, Graduate School of Health and Welfare Sciences, International University of Health and Welfare, Otawara, Tochigi, 324-8501, Japan.
Hideshi ShibataLaboratory of Veterinary Anatomy, Institute of Agriculture, Tokyo University of Agriculture and Technology, Fuchu, Tokyo, 183-8509, Japan.
Mieko KurosawaCenter for Medical Science, International University of Health and Welfare, 2600-1 Kitakanemaru, Otawara, Tochigi, 324-8501, Japan. mieko-ku@iuhw.ac.jp.ORCID http://orcid.org/0000-0002-7468-3081
International University of Health and Welfare · JPTokyo University of Agriculture and Technology · JP

Funding

JSPS KAKENHI Grant 16K01465
6 · The paper itself

Abstract

Noxious cutaneous stimulation increases, whereas innocuous cutaneous stimulation decreases serotonin (5-HT) release in the central nucleus of the amygdala (CeA) in anesthetized rats. In the present study, we investigated the contribution of corticotropin releasing factor (CRF) receptors and gamma-aminobutyric acid (GABA) receptors in the dorsal raphe nucleus (DRN) to those responses. Release of 5-HT in the CeA was monitored by microdialysis before and after 10-min stimulation by pinching or stroking. Increased 5-HT release in the CeA in response to pinching was abolished by CRF

Indexed as

AnimalsCentral Amygdaloid NucleusCorticotropin-Releasing HormoneDorsal Raphe Nucleusgamma-Aminobutyric AcidMalePeptide FragmentsPhysical StimulationRatsRats, WistarReceptors, GABA-ASerotoninSignal TransductionCorticotropin-Releasing Hormonecorticotropin releasing hormone (9-41)gamma-Aminobutyric AcidPeptide FragmentsReceptors, GABA-ASerotoninCRF1 receptorCRF2 receptorGABAA receptorMicrodialysisPinchingStroking

Identifiers

PMID27744641
PMCPMC10718013
OpenAlexW2530305503

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.