Evidence map›Paper›PMID 27744611›Full record

ReviewCurrent genetics2017

CodY, a master integrator of metabolism and virulence in Gram-positive bacteria.

Shaun R Brinsmade

Abstract readReview
PubMed Publisher
In one paragraph

Review in Current genetics, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 70 papers.

0numbers the graph read from it
0cells of the map it votes in
70citing papers in PubMed
6.3field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

70 citing papers in PubMed, 86 citations in OpenAlex.

  1. InJournal of bacteriology · 2026
    Article
  2. Review
  3. mBio · 2026
    Article
  4. Article
  5. Article
  6. InbioRxiv : the preprint server for biology · 2026
    Article
  7. Article
  8. Article
  9. Review
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Review
  16. Article
  17. Article
  18. Phenotypic Variation inAntibiotics (Basel, Switzerland) · 2024
    Review
  19. ThebioRxiv : the preprint server for biology · 2024
    Article
  20. Mutations in thebioRxiv : the preprint server for biology · 2024
    Article

10 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

Shaun R BrinsmadeDepartment of Biology, Georgetown University, Washington, DC, USA. shaun.brinsmade@georgetown.edu.ORCID http://orcid.org/0000-0002-5381-2817
Georgetown University · US

Funding

Integrating Global Responses to Nutrient Limitation in Gram-positive BacteriaR00GM099893 · NIGMS · GEORGETOWN UNIVERSITY · PI BRINSMADE, SHAUN R · 2013 to 2015
$725k
NIGMS NIH HHS R00 GM099893
6 · The paper itself

Abstract

A growing body of evidence points to CodY, a global regulator in Gram-positive bacteria, as a critical link between microbial physiology and pathogenesis in diverse environments. Recent studies uncovering graded regulation of CodY gene targets reflect the true nature of this transcription factor controlled by ligands and reveal nutrient availability as a potentially critical factor in modulating pathogenesis. This review will serve to update the status of the field and raise new questions to be answered.

Indexed as

Amino Acids, Branched-ChainBacillus subtilisBacterial ProteinsGene Expression Regulation, BacterialProtein BindingRepressor ProteinsStaphylococcus aureusTranscription FactorsAmino Acids, Branched-ChainBacterial ProteinsCodY protein, Staphylococcus aureusRepressor ProteinsTranscription FactorsBranched-chain amino acidsCodYRegulationVirulence

Identifiers

PMID27744611
OpenAlexW2531355008

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.