Evidence map›Paper›PMID 27744558›Full record

ArticleApplied microbiology and biotechnology2017

High throughput microencapsulation of Bacillus subtilis in semi-permeable biodegradable polymersomes for selenium remediation.

Jacob Barlow, Kevin Gozzi, Chase P Kelley, Benjamin M Geilich, Thomas J Webster, Yunrong Chai, Srinivas Sridhar, Anne L van de Ven

Open access · greenAbstract read
In one paragraph

Article in Applied microbiology and biotechnology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 23 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 2 countries.

Jacob BarlowDepartment of Chemical Engineering, Northeastern University, Boston, MA, USA.
Kevin GozziDepartment of Biology, Northeastern University, Boston, MA, USA.
Chase P KelleyDepartment of Chemical Engineering, Northeastern University, Boston, MA, USA.
Benjamin M GeilichDepartment of Bioengineering, Northeastern University, Boston, MA, USA.
Thomas J WebsterDepartment of Chemical Engineering, Northeastern University, Boston, MA, USA.
Yunrong ChaiDepartment of Biology, Northeastern University, Boston, MA, USA.
Srinivas SridharDepartment of Physics, Northeastern University, 360 Huntington Ave, Boston, MA, 02115, USA.
Anne L van de VenDepartment of Physics, Northeastern University, 360 Huntington Ave, Boston, MA, 02115, USA. a.vandevenmoloney@neu.edu.
Northeastern University · USKing Abdulaziz University · SA

Funding

CaNCURE: Cancer Nanomedicine Co-ops For Undergraduate Research ExperiencesR25CA174650 · NCI · NORTHEASTERN UNIVERSITY · PI SRINIVAS SRIDHAR · 2014 to 2026
$3.4M
NCI NIH HHS R25 CA174650
6 · The paper itself

Abstract

Encapsulating bacteria within constrained microenvironments can promote the manifestation of specialized behaviors. Using double-emulsion droplet-generating microfluidic synthesis, live Bacillus subtilis bacteria were encapsulated in a semi-permeable membrane composed of poly(ethylene glycol)-b-poly(D,L-lactic acid) (mPEG-PDLLA). This polymer membrane was sufficiently permeable to permit exponential bacterial growth, metabolite-induced gene expression, and rapid biofilm growth. The biodegradable microparticles retained structural integrity for several days and could be successfully degraded with time or sustained bacterial activity. Microencapsulated B. subtilis successfully captured and contained sodium selenite added outside the polymersomes, converting the selenite into elemental selenium nanoparticles that were selectively retained inside the polymer membrane. This remediation of selenium using polymersomes has high potential for reducing the toxicity of environmental selenium contamination, as well as allowing selenium to be harvested from areas not amenable to conventional waste or water treatment.

Indexed as

Bacillus subtilisBiodegradable PlasticsBiodegradation, EnvironmentalDrug CompoundingSeleniumBiodegradable PlasticsSeleniumBacteriaBiofilmDouble-emulsionMicrofluidicsMicroparticlesNanoparticlesSelenite

Identifiers

PMID27744558
PMCPMC5203941
OpenAlexW2530594408

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.