ReviewCurrent osteoporosis reports2016
Epidemiology of Skeletal Health in Type 1 Diabetes.
Review in Current osteoporosis reports, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
34 citing papers in PubMed, 3 syntheses or guidelines pooled it, 60 citations in OpenAlex.
- The diabetic neuropathy and bone mineral density in type 2 diabetes mellitus: a cross-sectional and meta-analytic study.Clinical and experimental medicine · 2025Pooled it
- Trabecular bone score in adults with type 1 diabetes: a meta-analysis.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2024Pooled it
- Pooled it
- Observational
- Bone Benefits After Simultaneous Pancreas-kidney Transplantation Compared With the Pretransplant Period.Transplantation · 2026Article
- Diabetes and osteoporosis: a two-sample mendelian randomization study.BMC musculoskeletal disorders · 2024Article
- The multi-faceted nature of age-associated osteoporosis.Bone reports · 2024Review
- Sarm1 knockout prevents type 1 diabetic bone disease in females independent of neuropathy.JCI insight · 2024Article
- A Causal Relationship Between Type 1 Diabetes and Risk of Osteoporosis: A Univariable and Multivariable Mendelian Randomization Study.Journal of diabetes research · 2024Article
- Glycemic Control and Bone in Diabetes.Current osteoporosis reports · 2022Review
- Single-cell RNA sequencing analysis reveals the relationship of bone marrow and osteopenia in STZ-induced type 1 diabetic mice.Journal of advanced research · 2022Article
- The evaluation of muscle strength and architecture in type 1 diabetes mellitus: a cross-sectional study.BMC endocrine disorders · 2022Article
- The effect of insulin and kruppel like factor 10 on osteoblasts in the dental implant osseointegration in diabetes mellitus patients.Bioengineered · 2022Article
- Structural Changes in Primary Teeth of Diabetic Children: Composition and Ultrastructure Analysis.Children (Basel, Switzerland) · 2022Article
- Immune-Protective Formulations and Process Strategies for Improved Survival and Function of Transplanted Islets.Frontiers in immunology · 2022Review
- Mechanisms of altered bone remodeling in children with type 1 diabetes.World journal of diabetes · 2021Review
- Diabetes mellitus accelerates the progression of osteoarthritis in streptozotocin-induced diabetic mice by deteriorating bone microarchitecture, bone mineral composition, and bone strength of subchondral bone.Annals of translational medicine · 2021Article
- Relationship between bone turnover markers and oxidative stress in children with type 1 diabetes mellitus.Pediatric research · 2021Article
- Article
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
The skeleton is adversely affected by type 1 diabetes (T1D). Patients with T1D of both sexes have an increased risk of fracture that begins in childhood and extends across the entire lifespan. T1D is characterized by mild to modest deficits in bone density, structure, and microarchitecture. Current evidence suggests that the observed bone deficits in T1D are the result of impaired bone formation rather than increased bone resorption. There is emerging data that bone quality is impaired in T1D, which may explain the findings that fracture risk is elevated out of proportion to the degree of bone mineral deficit. In this review, we summarize the current knowledge regarding the epidemiology of skeletal health in T1D. Given the high individual and societal burden of osteoporotic fracture, there is an urgent need to better understand the etiology of T1D-related bone disease so that clinical strategies to prevent fracture can be developed.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.