ReviewCurrent obesity reports2016
Effects of Obesity on Cardiovascular Hemodynamics, Cardiac Morphology, and Ventricular Function.
Review in Current obesity reports, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 140 papers, 4 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
140 citing papers in PubMed, 4 syntheses or guidelines pooled it, 282 citations in OpenAlex.
- Comparing GLP-1 agonists versus other weight loss interventions on risk of atrial fibrillation recurrence after catheter ablation: a meta-analysis.Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing · 2026Pooled it
- Evidence of Bariatric Surgery Benefits Cardiac Function in Non-HFpEF Patients with Obesity: a Meta-Analysis.Obesity surgery · 2023Pooled it
- Body Mass Index and the Risk of Atrial Fibrillation: A Mendelian Randomization Study.Nutrients · 2022Pooled it
- Effects of Bariatric Surgery on Heart Rhythm Disorders: a Systematic Review and Meta-Analysis.Obesity surgery · 2021Pooled it
- Changes in Kidney Fat upon Dietary-Induced Weight Loss.Nutrients · 2022Trial
- Sex-Related Differences in Brain Volumes and Cerebral Blood Flow Among Overweight and Obese Adults With Type 2 Diabetes: Exploratory Analyses From the Action for Health in Diabetes Brain Magnetic Resonance Imaging Study.The journals of gerontology. Series A, Biological sciences and medical sciences · 2020Trial
- Perioperative goal-directed fluid management using noninvasive hemodynamic monitoring in gynecologic oncology.Brazilian journal of anesthesiology (Elsevier)Trial
- Even short-term obesity leads to subclinical dysfunction of both ventricles in young individuals.Wiener klinische Wochenschrift · 2026Article
- Suboptimal Echocardiographic Image Quality Predicts in-Hospital Mortality Across the Adult Age Spectrum, Independent of Admission Type: A Large-Scale NLP Study.Echocardiography (Mount Kisco, N.Y.) · 2026Article
- Subclinical left ventricular diastolic dysfunction in adults with overweight or obesity and preserved ejection fraction.Obesity pillars · 2026Article
- ECMO for patients with obesity: evidence and practice.Intensive care medicine · 2026Review
- Review
- High-intensity interval training improves myocardial work and cardiac function in women with obesity: a randomized controlled study.International journal of obesity (2005) · 2026Article
- SLIT2 and ANGPTL3 as putative mediators linking obesity to atrial fibrillation: A Mendelian randomization study.Medicine · 2026Article
- Short-Term Cardiac Effects of Bariatric Surgery: Is Weight Loss Alone Sufficient in Metabolically Healthy Morbidly Obese Patients?Journal of cardiovascular development and disease · 2026Article
- Article
- Role of adipose tissue in cardiovascular health and diseases.Chinese medical journal · 2026Review
- High-fat diet feeding induces organ-specific vascular remodeling with distinct temporal dynamics in male mice.Communications biology · 2026Article
- Complementary assessment of cardiopulmonary morphometric changes in COPD using 3D multidetector computed tomography: relationship with functional indices.BMC pulmonary medicine · 2026Article
- Right ventricular function in pulmonary hypertension and obesity: a cross-sectional cohort study with survival follow-up.Clinical research in cardiology : official journal of the German Cardiac Society · 2026Article
80 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Obesity produces a variety of hemodynamic alterations that may cause changes in cardiac morphology which predispose to left and right ventricular dysfunction. Various neurohormonal and metabolic alterations commonly associated with obesity may contribute to these abnormalities of cardiac structure and function. These changes in cardiovascular hemodynamics, cardiac morphology, and ventricular function may, in severely obese patients, predispose to heart failure, even in the absence of other forms of heart disease (obesity cardiomyopathy). In normotensive obese patients, cardiac involvement is commonly characterized by elevated cardiac output, low peripheral vascular resistance, and increased left ventricular (LV) end-diastolic pressure. Sleep-disordered breathing may lead to pulmonary arterial hypertension and, in association with left heart failure, may contribute to elevation of right heart pressures. These alterations, in association with various neurohormonal and metabolic abnormalities, may produce LV hypertrophy; impaired LV diastolic function; and less commonly, LV systolic dysfunction. Many of these alterations are reversible with substantial voluntary weight loss.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.