Evidence map›Paper›PMID 27744005›Full record

ArticleClinical biomechanics (Bristol, Avon)2016

Paravertebral spinal injection for the treatment of patients with degenerative facet osteoarthropathy: Evidence of motor performance improvements based on objective assessments.

Nima Toosizadeh, Homayoon Harati, Tzu-Chuan Yen, Cindy Fastje, Jane Mohler, Bijan Najafi, Michael Dohm

Open access · greenAbstract read
In one paragraph

Article in Clinical biomechanics (Bristol, Avon), 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.0field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 9 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Nima ToosizadehArizona Center on Aging, Department of Medicine, University of Arizona, Tucson, AZ, USA; Interdisciplinary Consortium on Advanced Motion Performance (iCAMP), Department of Surgery, College of Medicine, University of Arizona, Tucson, AZ, USA.
Homayoon HaratiInterdisciplinary Consortium on Advanced Motion Performance (iCAMP), Department of Surgery, College of Medicine, University of Arizona, Tucson, AZ, USA.
Tzu-Chuan YenInterdisciplinary Consortium on Advanced Motion Performance (iCAMP), Department of Surgery, College of Medicine, University of Arizona, Tucson, AZ, USA; Department of Physiology, College of Medicine, University of Arizona, Tucson, AZ, USA.
Cindy FastjeDepartment of Orthopaedic Surgery, College of Medicine, University of Arizona, Tucson, AZ, USA.
Jane MohlerArizona Center on Aging, Department of Medicine, University of Arizona, Tucson, AZ, USA; Interdisciplinary Consortium on Advanced Motion Performance (iCAMP), Department of Surgery, College of Medicine, University of Arizona, Tucson, AZ, USA.
Bijan NajafiArizona Center on Aging, Department of Medicine, University of Arizona, Tucson, AZ, USA; Interdisciplinary Consortium on Advanced Motion Performance (iCAMP), Department of Surgery, College of Medicine, University of Arizona, Tucson, AZ, USA; Interdisciplinary Consortium on Advanced Motion Performance (iCAMP), Michael E. DeBakey Department of Surgery, Baylor College of Medicine, Houston, TX, USA. Electronic address: najafi.bijan@gmail.com.
Michael DohmDepartment of Orthopaedic Surgery, College of Medicine, University of Arizona, Tucson, AZ, USA.
University of Arizona · US

Funding

Phase II STTR: Portable Device for Telecare Monitoring of Elderly PeopleR42AG032748 · NIA · BIOSENSICS, LLC · PI GWIN, JOSEPH T, MOHLER, MARTHA JANE · 2012 to 2016
$2.7M
Portable Device for Telecare Monitoring of Elderly PeopleR41AG032748 · NIA · BIOSENSICS, LLC · PI NAJAFI, BIJAN · 2009 to 2009
$100k
NIA NIH HHS R41 AG032748NIA NIH HHS R42 AG032748
6 · The paper itself

Abstract

backgroundThis study examined short- and long-term improvements in motor performance, quantified using wearable sensors, in response to facet spine injection in degenerative facet osteoarthropathy patients.

methodsAdults with confirmed degenerative facet osteoarthropathy were recruited and were treated with medial or intermediate branch block injection. Self-report pain, health condition, and disability (Oswestry), as well as objective motor performance measures (gait, balance, and timed-up-and-go) were obtained in five sessions: pre-surgery (baseline), immediately after the injection, one-month, three-month, and 12-month follow-ups. Baseline motor performance parameters were compared with 10 healthy controls.

findingsThirty patients (age=50 (14) years) and 10 controls (age=46 (15) years) were recruited. All motor performance parameters were significantly different between groups. Results showed that average pain and Oswestry scores improved by 51% and 24%, respectively among patients, only one month after injection. Similarly, improvement in motor performance was most noticeable in one-month post-injection measurements; most improvements were observed in gait speed (14% normal walking, P<0.02), hip sway within balance tests (63% eyes-open P<0.01), and turning velocity within the timed-up-and-go test (28%, P<0.02). Better baseline motor performance led to better outcomes in terms of pain relief; baseline turning velocity was 18% faster among the responsive compared to the non-responsive patients. INTERPRETATIONS: Spinal injection can temporarily (one to three months) improve motor performance in degenerative facet osteoarthropathy patients. Successful pain relief in response to treatment is independent of demographic characteristics and initial pain but dependent on baseline motor performance. Immediate self-reported pain relief is unrelated to magnitude of gradual improvement in motor performance.

Indexed as

Anesthetics, LocalBupivacaineFemaleGaitGlucocorticoidsHumansInjections, SpinalLidocaineLow Back PainMaleMiddle AgedMotor ActivityOsteoarthritis, SpinePostural BalanceTreatment OutcomeTriamcinoloneAnesthetics, LocalBupivacaineGlucocorticoidsLidocaineTriamcinoloneBalanceLow back painMotor performanceOsteoarthropathySpine injectionWearable technology

Identifiers

PMID27744005
PMCPMC5159257
OpenAlexW2531834986

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.