ReviewThe lancet. Diabetes & endocrinology2016
Preconceptional and maternal obesity: epidemiology and health consequences.
Review in The lancet. Diabetes & endocrinology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 564 papers, 10 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
564 citing papers in PubMed, 10 syntheses or guidelines pooled it, 1,077 citations in OpenAlex.
- Impact of Maternal Underweight on Infant and Maternal Outcomes in Japanese Women: A Systematic Review and Meta-analysis.Journal of epidemiology · 2026Pooled it
- Comparison of neuraxial anesthesia and analgesia strategies for obese parturients: a systematic review and network meta-analysis.BMC anesthesiology · 2026Pooled it
- Maternal obesity and the risk of neonatal sepsis: a meta-analysis.Frontiers in pediatrics · 2026Pooled it
- Validity of non-traditional measures of obesity compared to total body fat across the life course: A systematic review and meta-analysis.Obesity reviews : an official journal of the International Association for the Study of Obesity · 2025Pooled it
- The effect of methods used in the management of maternal obesity on pregnancy and birth outcomes: a systematic review with meta-analysis.International journal of obesity (2005) · 2025Pooled it
- Relationship Between Improvements in Glycemic Control and Risk of Pregnancy Complications in Patients With Diabetes Mellitus: Metaregression Analysis of Randomized Controlled Trials of Intensive Glucose Management.Journal of diabetes research · 2025Pooled it
- Maternal adiposity and perinatal and offspring outcomes: an umbrella review.Nature human behaviour · 2024Pooled it
- A Systematic Review of Methods and Practice for Integrating Maternal, Fetal, and Child Health Outcomes, and Family Spillover Effects into Cost-Utility Analyses.PharmacoEconomics · 2024Pooled it
- Effects of mHealth-Based Lifestyle Interventions on Gestational Diabetes Mellitus in Pregnant Women With Overweight and Obesity: Systematic Review and Meta-Analysis.JMIR mHealth and uHealth · 2024Pooled it
- Influence of maternal body mass index on pregnancy complications and outcomes: a systematic review and meta-analysis.Frontiers in endocrinology · 2024Pooled it
- Predictors of Infection after Cesarean Delivery.American journal of perinatology · 2026Trial
- Evaluating wearable-supported exercise interventions for reducing postpartum weight: a randomized controlled trial.BMC pregnancy and childbirth · 2026Trial
- Associations between lifestyle and well-being in early and late pregnancy in women with overweight or obesity: Secondary analyses of the PEARS RCT.British journal of health psychology · 2025Trial
- Motivations for and experience with labor induction at 39 weeks in women with obesity-A qualitative study.Acta obstetricia et gynecologica Scandinavica · 2025Trial
- Trial
- Diet quality and blood pressure among pregnant women with overweight or obesity: A secondary analysis of two randomized controlled trials.Acta obstetricia et gynecologica Scandinavica · 2024Trial
- Preconception Micronutrient Supplementation Affects Maternal BMI and Body Composition Postpartum: A Randomized Controlled Trial in Vietnam.The Journal of nutrition · 2024Trial
- Effect of the smartphone application on caesarean section in women with overweight and obesity: a randomized controlled trial in China.BMC pregnancy and childbirth · 2023Trial
- Longitudinal modelling of microbiome subcommunities reveals parity-dependent dynamics during pregnancy and postpartum.Gut microbes · 2026Article
- Gut microbiome and pregnancy complications: emerging evidence and mechanistic insights.Gut microbes · 2026Review
504 more citing papers are in PubMed but not listed here.
Corrections and comments
- Commented on by
Authors and funding
7 authors at 7 institutions in 4 countries.
Funding
Abstract
Obesity in women of reproductive age is increasing in prevelance worldwide. Obesity reduces fertility and increases time taken to conceive, and obesity-related comorbidities (such as type 2 diabetes and chronic hypertension) heighten the risk of adverse outcomes for mother and child if the woman becomes pregnant. Pregnant women who are obese are more likely to have early pregnancy loss, and have increased risk of congenital fetal malformations, delivery of large for gestational age infants, shoulder dystocia, spontaneous and medically indicated premature birth, and stillbirth. Late pregnancy complications include gestational diabetes and pre-eclampsia, both of which are associated with long-term morbidities post partum. Women with obesity can also experience difficulties during labour and delivery, and are more at risk of post-partum haemorrhage. Long-term health risks are associated with weight retention after delivery, and inherent complications for the next pregnancy. The wellbeing of the next generation is also compromised. All these health issues could be avoided by prevention of obesity among women of reproductive age, which should be viewed as a global public health priority. For women who are already obese, renewed efforts should be made towards improved management during pregnancy, especially of blood glucose, and increased attention to post-partum weight management. Effective interventions, tailored to ethnicity and culture, are needed at each of these stages to improve the health of women and their children in the context of the global obesity epidemic.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.