Evidence map›Paper›PMID 27743685›Full record

ReviewTrends in cognitive sciences2016

Oscillatory Dynamics of Prefrontal Cognitive Control.

Randolph F Helfrich, Robert T Knight

Abstract readReview
In one paragraph

Review in Trends in cognitive sciences, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 162 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
162citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

162 citing papers in PubMed, 1 synthesis or guideline pooled it.

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  15. Dynamic Modulation of Beta-Band Oscillations in the LGN and Their Role in Visual Processing.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2026
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102 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Randolph F HelfrichHelen Wills Neuroscience Institute, UC Berkeley, 132 Barker Hall, Berkeley, CA 94720, USA; Department of Psychology, University of Oslo, Forskningsveien 3A, 0373 Oslo, Norway; Department of Neurophysiology and Pathophysiology, University Medical Center Hamburg-Eppendorf, Martinistr. 52, 20246 Hamburg, Germany. Electronic address: rhelfrich@berkeley.edu.
Robert T KnightHelen Wills Neuroscience Institute, UC Berkeley, 132 Barker Hall, Berkeley, CA 94720, USA; Department of Psychology, UC Berkeley, Tolman Hall, Berkeley, CA 94720, USA.

Funding

Attention, Orientation and the Human Prefrontal CortexR01NS021135 · NINDS · UNIVERSITY OF CALIFORNIA DAVIS · PI Robert Thomas Knight · 1985 to 2026
$6.5M
ATTENTION, ORIENTATION, & THE HUMAN PREFRONTAL CORTEXR37NS021135 · NINDS · UNIVERSITY OF CALIFORNIA BERKELEY · PI KNIGHT, ROBERT THOMAS · 2013 to 2019
$3.6M
NINDS NIH HHS R01 NS021135NINDS NIH HHS R37 NS021135
6 · The paper itself

Abstract

The prefrontal cortex (PFC) provides the structural basis for numerous higher cognitive functions. However, it is still largely unknown which mechanisms provide the functional basis for flexible cognitive control of goal-directed behavior. Here, we review recent findings that suggest that the functional architecture of cognition is profoundly rhythmic and propose that the PFC serves as a conductor to orchestrate task-relevant large-scale networks. We highlight several studies that demonstrated that oscillatory dynamics, such as phase resetting, cross-frequency coupling (CFC), and entrainment, support PFC-dependent recruitment of task-relevant regions into coherent functional networks. Importantly, these findings support the notion that distinct spectral signatures reflect different cortical computations supporting effective multiplexing on different temporal channels along the same anatomical pathways.

Indexed as

PeriodicityPrefrontal CortexCognitionHumanscross-frequency couplinglarge-scale networksnetwork connectivityneuronal entrainmentneuronal oscillationsprefrontal cortex

Identifiers

PMID27743685
PMCPMC5127407

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.